{"id":60268,"date":"2025-11-05T18:24:10","date_gmt":"2025-11-05T18:24:10","guid":{"rendered":"https:\/\/discover.restek.com\/?p=60268"},"modified":"2026-01-08T14:20:59","modified_gmt":"2026-01-08T14:20:59","slug":"cannabis-potency-testing-which-column-dimension-is-right-for-you","status":"publish","type":"post","link":"https:\/\/discover.restek.com\/de\/posters-presentations-ja\/gnot5282\/cannabis-potency-testing-which-column-dimension-is-right-for-you","title":{"rendered":"Cannabis Potency Testing\u2014Which Column Dimension is Right for You?"},"content":{"rendered":"\n<p>When starting method development for potency testing, it\u2019s important to choose the right column dimension for the target analysis. In this work, different column dimensions of the Raptor ARC-18 phase were utilized to develop methods to meet various labs\u2019 needs using HPLC-UV. To demonstrate the powerful resolving capabilities of Raptor ARC-18, a 50 x 3 mm, 2.7 \u00b5m column was used to analyze 7 cannabinoids including CBD, CBDA, delta-9-THC, delta-8-THC, (6aR, 9S)-delta-10-THC, (6aR, 9R)-delta-10-THC, and THCA. Next, additional cannabinoids including CBDV, THCV, CBG, CBN, CBGA, and CBC were added to the previous analytes for a total of 13 cannabinoids. Using the same column dimension and mobile phases, a method was developed to resolve all analytes in 10 minutes. Finally, to include exo-THC and CBNA, a 150 x 3 mm, 2.7 \u00b5m column dimension was used to demonstrate the utility of a longer column dimension. Each of these methods was applied to hemp matrix to demonstrate the applicability of these methods in real-world samples.<\/p>\n\n\n\n<div data-wp-interactive=\"core\/file\" class=\"wp-block-file\"><object data-wp-bind--hidden=\"!state.hasPdfPreview\" hidden class=\"wp-block-file__embed\" data=\"https:\/\/discover.restek.com\/wp-content\/uploads\/poster-cannabis-potency-testing-which-column-dimension-is-right-for-you.pdf\" type=\"application\/pdf\" style=\"width:100%;height:600px\" aria-label=\"Embed of poster-cannabis-potency-testing-which-column-dimension-is-right-for-you.\"><\/object><a id=\"wp-block-file--media-6c3de485-1884-48d5-bc5d-ef560a882f88\" href=\"https:\/\/discover.restek.com\/wp-content\/uploads\/poster-cannabis-potency-testing-which-column-dimension-is-right-for-you.pdf\">poster-cannabis-potency-testing-which-column-dimension-is-right-for-you<\/a><a href=\"https:\/\/discover.restek.com\/wp-content\/uploads\/poster-cannabis-potency-testing-which-column-dimension-is-right-for-you.pdf\" class=\"wp-block-file__button wp-element-button\" download aria-describedby=\"wp-block-file--media-6c3de485-1884-48d5-bc5d-ef560a882f88\">Download<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>When starting method development for potency testing, it\u2019s important to choose the right column dimension for the target analysis. In this work, different column dimensions of the Raptor ARC-18 phase were utilized to develop methods to meet various labs\u2019 needs using HPLC-UV. To demonstrate the powerful resolving capabilities of Raptor ARC-18, a 50 x 3 mm, 2.7 \u00b5m column was used to analyze 7 cannabinoids including CBD, CBDA, delta-9-THC, delta-8-THC, (6aR, 9S)-delta-10-THC, (6aR, 9R)-delta-10-THC, and THCA. Next, additional cannabinoids including CBDV, THCV, CBG, CBN, CBGA, and CBC were added to the previous analytes for a total of 13 cannabinoids. Using the same column dimension and mobile phases, a method was developed to resolve all analytes in 10 minutes. Finally, to include exo-THC and CBNA, a 150 x 3 mm, 2.7 \u00b5m column dimension was used to demonstrate the utility of a longer column dimension. Each of these methods was applied to hemp matrix to demonstrate the applicability of these methods in real-world samples.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"footnotes":""},"categories":[810],"tags":[],"industries-application":[],"post-badge":[],"resource-type":[],"product-library":[],"resource-technique":[],"hf_cat_post":[2642],"ppma_author":[648],"class_list":["post-60268","post","type-post","status-publish","format-standard","hentry","category-posters-presentations-ja"],"acf":[],"taxonomy_info":{"category":[{"value":810,"label":"Posters &amp; Presentations"}]},"featured_image_src_large":false,"author_info":{"display_name":"Patrick Gallagher","author_link":"https:\/\/discover.restek.com\/de\/author\/patrick-gallagherrestek-com\/"},"comment_info":0,"category_info":[{"term_id":810,"name":"Posters &amp; Presentations","slug":"posters-presentations-ja","term_group":0,"term_taxonomy_id":810,"taxonomy":"category","description":"","parent":0,"count":118,"filter":"raw","cat_ID":810,"category_count":118,"category_description":"","cat_name":"Posters &amp; Presentations","category_nicename":"posters-presentations-ja","category_parent":0}],"tag_info":false,"authors":[{"term_id":648,"user_id":0,"is_guest":1,"slug":"dan-delurio","display_name":"Dan DeLurio","avatar_url":"https:\/\/secure.gravatar.com\/avatar\/?s=96&d=mm&r=g","0":null,"1":"","2":"","3":"","4":"","5":"","6":"","7":"","8":""}],"_links":{"self":[{"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/posts\/60268","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/comments?post=60268"}],"version-history":[{"count":1,"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/posts\/60268\/revisions"}],"predecessor-version":[{"id":60270,"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/posts\/60268\/revisions\/60270"}],"wp:attachment":[{"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/media?parent=60268"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/categories?post=60268"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/tags?post=60268"},{"taxonomy":"industries-application","embeddable":true,"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/industries-application?post=60268"},{"taxonomy":"post-badge","embeddable":true,"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/post-badge?post=60268"},{"taxonomy":"resource-type","embeddable":true,"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/resource-type?post=60268"},{"taxonomy":"product-library","embeddable":true,"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/product-library?post=60268"},{"taxonomy":"resource-technique","embeddable":true,"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/resource-technique?post=60268"},{"taxonomy":"hf_cat_post","embeddable":true,"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/hf_cat_post?post=60268"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/discover.restek.com\/de\/wp-json\/wp\/v2\/ppma_author?post=60268"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}