FAQ

Where can I find a QuEChERS method for my application?

30 Jul 2025

QuEChERS, which stands for “Quick, Easy, Cheap, Effective, Rugged, and Safe,” is an increasingly popular approach to sample preparation for multiresidue pesticides analysis of a variety of food matrices. It is simpler and more streamlined than traditional liquid-liquid extractions and even easier than SPE. Three simple steps are involved with all QuEChERS methods: sample homogenization, extraction, and cleanup using dSPE tubes.

QuEChERS sample preparation for many analyses can be done by using the Original Unbuffered Method, which is the simplest procedure. Additionally, several buffered methods exist, which can improve recoveries for pH-sensitive pesticides. The most widely adopted buffered methods are EN 15662Mini-Multiresidue, and AOAC 2007.01.

Download Restek’s QuEChERS guide for an illustration of method steps, example applications, and a selection guide that shows exactly which dSPE tubes and sorbents are needed for each of the primary QuEChERS methods, including dSPE tubes for generic or universal use. In addition, validation and proficiency data for the QuEChERS method are available for a wide variety of pesticides in several common food matrices at www.quechers.eu. Restek’s ChromaBLOGraphy is also a good source for a variety of QuEChERS applications. Use “QuEChERS” as a keyword to search for relevant blog articles.

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  • Restek Corporation

    Restek is a leading provider of chromatography columns, accessories, and certified reference materials. Trust Restek for reliable, high-quality analytical solutions.

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