The Raptor Biphenyl is made with superficially porous particles of silica, often abbreviated as SPP. The SPP silica has a solid core with a porous outer layer and is made with a diameter that is typical of HPLC particles, in this case, 2.7 µm. SPP columns exhibit higher efficiencies and resolution, often approaching that of smaller (such as 1.9 µm) UHPLC particles that are based on fully porous silica. There are also a couple of additional benefits to using solid core particles. SPP silica particles can be operated at high flow rates without significantly impacting column resolution, and they do not require higher pressure system components like UHPLC columns do. (It’s nice to achieve a separation that looks like UHPLC on a regular HPLC system!)
How does the new Raptor Biphenyl column differ from other Biphenyl columns from Restek?
31 Jul 2025
Author
GNOT5059
