FAQ

Why are amines tailing on my capillary GC column?

31 Jul 2025

Poor chromatography and/or response for amines often are the result of contact between acidic silanol groups (acidic active sites) and the amines (basic compounds). This interaction can take place within the injection port or in the column. The most efficient way to counteract this negative effect is to use a base-deactivated injection port liner and a base-deactivated column. Restek offers base-deactivated liners and base-deactivated columns in three polarities: Rtx-Volatile Amine and Rtx-5 Amine columns are low-polarity, Rtx-35 Amine columns are moderately polar, and Stabilwax-DB columns are highly polar. All are designed to reduce tailing of basic compounds.

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GNOT5017