Capillary columns can produce a varying amount of baseline noise (siloxane bleed), usually containing fragment ions at m/z 73, 207, and 281, but they will not produce any distinct peaks in an analytical run. The most common sources of distinct siloxane peaks are septum bleed and the chemicals used to deactivate the injection port liner and the glass wool packing material.
I see ghost peaks when I inject a sample or standard, and my mass spectrometer identifies these peaks as some form of siloxane material. Is there a problem with my column?
31 Jul 2025
Author
GNOT5019
