Posters & Presentations

A Virtual Liquid Chromatography Method Development Tool for Cannabinoid Analysis

22 Jan 2026

The development and optimization of cannabinoid separations can be time-consuming and costly, often requiring a number of steps including method scouting, development, and optimization. To reduce cost and save time, an instrument-free software modeling tool was developed. This allows users to select compounds from a database, and instantly model a separation by adjusting parameters, such as instrument/system effects (dwell and extra column volume), temperature, and mobile phase additives. The modeler delivers a fast, no-cost starting point for LC method developers, both novice, and expert, who lack the expertise or the time to develop and optimize separations quickly and accurately. This novel, virtual method development software can improve turnaround time, increase throughput to existing methods, and offer an on-demand consultative user experience.

Author

  • Melinda Ulrich

    Melinda “Mel” Urich is an applications scientist in the LC Solutions department. Her primary focus is on the development of novel applications in the cannabis and food markets. In her previous role at Restek as an LC manufacturing chemist, she led the synthesis of silica, bonding of stationary phases as well as new process implementations and improvements. Mel attended Juniata College where she earned her BS in Chemistry and performed research in Atomic Force Microscopy AFM).

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