{"id":105417,"date":"2026-01-19T19:41:14","date_gmt":"2026-01-19T19:41:14","guid":{"rendered":"https:\/\/discover.restek.com\/?p=105417"},"modified":"2026-10-16T12:57:43","modified_gmt":"2026-10-16T12:57:43","slug":"obtenez-des-limites-de-detection-plus-basses-pour-les-composes-semi-volatils","status":"publish","type":"post","link":"https:\/\/discover.restek.com\/fr\/articles-fr\/evan5255\/obtenez-des-limites-de-detection-plus-basses-pour-les-composes-semi-volatils","title":{"rendered":"Obtenez des limites de d\u00e9tection plus basses pour les compos\u00e9s semi-volatils"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\"><strong><em>\u00c9l\u00e9ments cl\u00e9s<\/em><\/strong><\/h2>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<ul class=\"wp-block-list\">\n<li>La d\u00e9sactivation TriMax extr\u00eamement efficace des colonnes GC, produit un circuit d&#8217;\u00e9chantillon exceptionnellement inerte pour les compos\u00e9s acides, basiques et neutres.<\/li>\n\n\n\n<li>L&#8217;inertie maximale se traduit par une sensibilit\u00e9 optimale pour une large gamme de compos\u00e9s semi-volatils difficiles \u00e0 analyser.<\/li>\n\n\n\n<li>Par rapport \u00e0 une colonne premium concurrente, la colonne RMX-5Sil MS a permis d&#8217;obtenir une MDL plus basse pour 60 % et une LLOQ plus basse pour 63 % des 52 compos\u00e9s test\u00e9s.<\/li>\n<\/ul>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/explore.restek.com\/RMX-contact-technical-service-fr\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"127\" src=\"https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-Contact-us-HTML-Block-TECHNICAL-SERVICE_FR-768x127-2.png\" alt=\"\" class=\"wp-image-83953\" title=\"-\" srcset=\"https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-Contact-us-HTML-Block-TECHNICAL-SERVICE_FR-768x127-2.png 768w, https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-Contact-us-HTML-Block-TECHNICAL-SERVICE_FR-768x127-2-300x50.png 300w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \/><\/a><\/figure>\n<\/div>\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/explore.restek.com\/RMX-contact-sales-fr\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"127\" src=\"https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-Contact-us-HTML-Block-SALES-FR-768x127-1.png\" alt=\"\" class=\"wp-image-83959\" title=\"-\" srcset=\"https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-Contact-us-HTML-Block-SALES-FR-768x127-1.png 768w, https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-Contact-us-HTML-Block-SALES-FR-768x127-1-300x50.png 300w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \/><\/a><\/figure>\n<\/div>\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>R\u00e9sum\u00e9<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Cette \u00e9tude examine l&#8217;impact de la d\u00e9sactivation de colonne GC sur l&#8217;abaissement des limites de d\u00e9tection pour l&#8217;analyse des compos\u00e9s semi-volatils par GC-MS\/MS. Les MDL et LLOQ obtenues avec une colonne RMX-5Sil MS se sont r\u00e9v\u00e9l\u00e9es nettement plus basses pour environ deux tiers des compos\u00e9s test\u00e9s, par rapport \u00e0 une colonne premium concurrente.La d\u00e9sactivation efficace des colonnes RMX-5Sil MS a permis d&#8217;atteindre une meilleure sensibilit\u00e9 pour une large gamme de compositions chimiques.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Introduction<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">La quantification pr\u00e9cise des compos\u00e9s organiques semi-volatils \u00e0 l&#8217;\u00e9tat de traces dans les matrices environnementales est essentielle pour \u00e9valuer la contamination, assurer la conformit\u00e9 r\u00e9glementaire et estimer les risques pour la sant\u00e9 humaine et l&#8217;environnement. La GC-MS\/MS constitue une technique de r\u00e9f\u00e9rence pour abaisser les limites de d\u00e9tection et de quantification des compos\u00e9s semi-volatils, gr\u00e2ce \u00e0 sa s\u00e9lectivit\u00e9 et \u00e0 sa sensibilit\u00e9 \u00e9lev\u00e9es. Une sensibilit\u00e9 accrue permet aux laboratoires d&#8217;adopter des m\u00e9thodes de pr\u00e9paration d&#8217;\u00e9chantillons alternatives, r\u00e9duisant les volumes d&#8217;extraction et, par cons\u00e9quent, la consommation de solvants chlor\u00e9s. La sensibilit\u00e9 d&#8217;une m\u00e9thode se caract\u00e9rise g\u00e9n\u00e9ralement par deux param\u00e8tres cl\u00e9s : la limite de d\u00e9tection de la m\u00e9thode (MDL) et la limite inf\u00e9rieure de quantification (LLOQ). La MDL correspond \u00e0 la concentration la plus basse pouvant \u00eatre distingu\u00e9e des r\u00e9sultats du blanc de m\u00e9thode et mesur\u00e9e avec un niveau de confiance de 99 %. La LLOQ, quant \u00e0 elle, d\u00e9finit la concentration la plus basse \u00e0 laquelle un laboratoire d\u00e9montre qu&#8217;un analyte peut \u00eatre quantifi\u00e9 avec une exactitude et une pr\u00e9cision acceptables.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Abaisser la MDL et la LLOQ dans les m\u00e9thodes GC-MS\/MS pour l&#8217;analyse des semi-volatils n\u00e9cessite d&#8217;optimiser de nombreux facteurs notamment la pr\u00e9paration des \u00e9chantillons, les techniques d&#8217;injection, les conditions chromatographiques ainsi que les param\u00e8tres du spectrom\u00e8tre de masse.<br>L&#8217;inertie du circuit de l&#8217;\u00e9chantillon joue \u00e9galement un r\u00f4le d\u00e9terminant dans l&#8217;abaissement de ces limites. Les fabricants de colonnes GC utilisent diff\u00e9rents proc\u00e9d\u00e9s de d\u00e9sactivation afin de rendre la surface de la colonne plus inerte et de limiter les interactions susceptibles de diminuer la sensibilit\u00e9 analytique, en particulier la d\u00e9gradation de la forme de pics. Toutefois, les d\u00e9sactivations classiques restent g\u00e9n\u00e9ralement plus efficaces pour certaines classes de compos\u00e9s que pour d&#8217;autres. Restek a d\u00e9velopp\u00e9 la d\u00e9sactivation TriMax de nouvelle g\u00e9n\u00e9ration, utilis\u00e9e sur l&#8217;ensemble des colonnes RMX, qui conf\u00e8re \u00e0 la surface une inertie exceptionnelle, efficace sur une large gamme de compositions chimiques de compos\u00e9s semi-volatils.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Cette \u00e9tude compare les limites de d\u00e9tection et de quantification pouvant \u00eatre atteintes avec une colonne RMX-5Sil MS et une colonne premium d&#8217;un autre fabricant, en \u00e9valuant les niveaux de MDL et de LLOQ. Les essais ont \u00e9t\u00e9 r\u00e9alis\u00e9s \u00e0 partir d&#8217;\u00e9talons pr\u00e9par\u00e9s dans un solvant plut\u00f4t que dans une matrice, afin d&#8217;\u00e9valuer sp\u00e9cifiquement la performance de la colonne, ind\u00e9pendamment des effets li\u00e9s li\u00e9s \u00e0 la pr\u00e9paration des \u00e9chantillons.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>M\u00e9thode exp\u00e9rimentale<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><em>Pr\u00e9paration des \u00e9talons et des \u00e9chantillons<\/em><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Les \u00e9talons d&#8217;\u00e9talonnage ont \u00e9t\u00e9 pr\u00e9par\u00e9s dans du chlorure de m\u00e9thyl\u00e8ne aux concentrations suivantes : 0,5, 1, 2, 5, 10, 20, 50, 100, 200, 500, 1000, 2000 et 5000 ppb. Pour les deux colonnes, les courbes d&#8217;\u00e9talonnage ont \u00e9t\u00e9 r\u00e9alis\u00e9es le premier jour, avec des injections en triplicat des \u00e9talons ayant une concentration allant de 0,5 \u00e0 100 ppb. La plage lin\u00e9aire de la courbe d&#8217;\u00e9talonnage a \u00e9t\u00e9 d\u00e9termin\u00e9e pour chaque compos\u00e9 semi-volatil en fonction de sa r\u00e9ponse analytique. Les jours 2 et 3, de nouveaux \u00e9talons de 0,5 \u00e0 100 ppb ont \u00e9t\u00e9 pr\u00e9par\u00e9s puis inject\u00e9s en triplicat afin de d\u00e9terminer la MDL et la LLOQ de chaque compos\u00e9 semi-volatil sur chacune des colonnes \u00e9valu\u00e9es.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><em>Conditions analytiques d&#8217;analyse par GC-MS\/MS<\/em><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Les \u00e9chantillons ont \u00e9t\u00e9 analys\u00e9s sur une colonne RMX-5Sil MS et sur une colonne premium concurrente, toutes deux de dimensions 30 m, DI 0,25 mm, 0,25 \u00b5m. Les analyses des compos\u00e9s voltails ont \u00e9t\u00e9 r\u00e9alis\u00e9s \u00e0 l&#8217;aide d&#8217;un GC Thermo TRACE 1310 coupl\u00e9 \u00e0 un spectrom\u00e8tre de masse TSQ 8000,selon les conditions ci-dessous.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Volume d&#8217;injection : 1 \u00b5L<br>Insert : insert d&#8217;injection Topaz Precision 4 mm avec laine (r\u00e9f. 23267)<br>I&#8217;injecteur : temp\u00e9rature d&#8217;injection 280 \u00b0C ; split 10:1 ; d\u00e9bit 1,2 mL\/min<br>Gaz vecteur : h\u00e9lium<br>Programme de la temp\u00e9rature du four : 40 \u00b0C (maintien 1 min) \u00e0 280 \u00b0C \u00e0 12 \u00b0C\/min puis \u00e0 310 \u00b0C \u00e0 3 \u00b0C\/min<br>D\u00e9tecteur : MS\/MS ; mode SRM ; temp\u00e9rature de la ligne de transfert 280 \u00b0C ; temp\u00e9rature de la source \u00e0 330 \u00b0C (voir le chromatogramme pour les transitions SRM)<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large has-custom-border\"><a href=\"https:\/\/discover.restek.com\/fr\/articles-fr\/gnot3445-fr\/outils-en-ligne-ezgc\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"238\" src=\"https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-EZGC-HTML-Block_FR-1024x238.png\" alt=\"Banni\u00e8re Logiciel EZGC\" class=\"wp-image-83968\" style=\"border-style:none;border-width:0px;border-top-left-radius:7px;border-top-right-radius:7px;border-bottom-left-radius:7px;border-bottom-right-radius:7px\" title=\"-\" srcset=\"https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-EZGC-HTML-Block_FR-1024x238.png 1024w, https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-EZGC-HTML-Block_FR-300x70.png 300w, https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-EZGC-HTML-Block_FR-768x179.png 768w, https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-EZGC-HTML-Block_FR.png 1340w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n<\/div>\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><em>\u00c9valuation de la qualit\u00e9 des donn\u00e9es<\/em><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Les MDL ont \u00e9t\u00e9 calcul\u00e9es pour chaque compos\u00e9, sur chaque colonne, en multipliant l&#8217;\u00e9cart-type de la concentration recalcul\u00e9e \u00e0 son point d&#8217;\u00e9talonnage le plus bas par t = 2,896 (n = 9). La LLOQ a \u00e9t\u00e9 d\u00e9termin\u00e9e \u00e0 partir des m\u00eames \u00e9chantillons et correspond au point d&#8217;\u00e9talonnage le plus bas pr\u00e9sentant un taux de r\u00e9cup\u00e9ration compris entre 80 et 120 % (ou le taux de r\u00e9cup\u00e9ration le plus proche disponible) pour chaque compos\u00e9 semi-volatil, sur chaque colonne.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>R\u00e9sultats et discussion<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">La MDL \u00e9tait plus basse sur la colonne RMX-5Sil MS pour 60 % (31\/52) des compos\u00e9s \u00e9valu\u00e9s (Tableau I, Figure 1). De m\u00eame, la LLOQ \u00e9tait plus basse sur la colonne RMX-5Sil MS pour 63 % (33\/52) des analytes cibl\u00e9s (Tableau I, Figure 2). Les r\u00e9sultats de chaque compos\u00e9 sont pr\u00e9sent\u00e9s dans le Tableau II. Des valeurs de MDL et de LLOQ plus basses traduisent une sensibilit\u00e9 accrue avec la colonne RMX-5Sil MS. Cette am\u00e9lioration peut \u00eatre attribu\u00e9e \u00e0 l&#8217;inertie sup\u00e9rieure obtenue gr\u00e2ce \u00e0 la nouvelle technologie de d\u00e9sactivation de surface de Restek. Il est important de noter que des limites de d\u00e9tection plus basses ont \u00e9t\u00e9 obtenues pour une large gamme de classes de compos\u00e9s, incluant les semi-volatils acides, basiques et neutres, avec la colonne RMX-5Sil MS.<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<style>.kb-image105417_c7c6af-e6 .kb-image-has-overlay:after{opacity:0.3;}<\/style>\n<div class=\"wp-block-kadence-image kb-image105417_c7c6af-e6\"><figure class=\"aligncenter size-large\"><a href=\"https:\/\/www.restek.com\/c\/1484\" class=\"kb-advanced-image-link\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"177\" src=\"https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-HTML-Block-with-Topaz-Liners-1024x177.png\" alt=\"ad for RMX columns and Topaz liners\" class=\"kb-img wp-image-89475\" title=\"-\" srcset=\"https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-HTML-Block-with-Topaz-Liners-1024x177.png 1024w, https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-HTML-Block-with-Topaz-Liners-300x52.png 300w, https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-HTML-Block-with-Topaz-Liners-768x133.png 768w, https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-HTML-Block-with-Topaz-Liners.png 1340w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Tableau I<\/strong> : Dans l&#8217;ensemble, les colonnes RMX-5Sil MS, hautement inertes, ont produit des LLOQ et des MDL plus basses pour un plus grand nombre de compos\u00e9s qu&#8217;une colonne premium concurrente. Elles permettent d&#8217;atteindre des limites de d\u00e9tection plus basses pour l&#8217;analyse des compos\u00e9s semi-volatils.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong>LLOQ (ppb)<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong>LLOQ (ppb)<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong>LLOQ (ppb)<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong>MDL (ppb<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong>MDL (ppb)<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong>MDL (ppb<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><\/th><\/tr><tr><th><strong>Colonne<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong>Moyenne<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong>Min<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong>Max<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong>RMX-5Sil offre les meilleures performances<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong><strong>Moyenne<\/strong><\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong>Min<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong>Max<\/strong><\/th><th class=\"has-text-align-center\" data-align=\"center\"><strong><strong>RMX-5Sil offre les meilleures performances<\/strong><\/strong><\/th><\/tr><\/thead><tbody><tr><td>RMX-5Sil MS<\/td><td class=\"has-text-align-center\" data-align=\"center\">14<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">100<\/td><td class=\"has-text-align-center\" data-align=\"center\">33\/52 compos\u00e9s (63%)<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.1<\/td><td class=\"has-text-align-center\" data-align=\"center\">14<\/td><td class=\"has-text-align-center\" data-align=\"center\">31\/52 compos\u00e9s (60%)<\/td><\/tr><tr><td>Colonne premium concurrente<\/td><td class=\"has-text-align-center\" data-align=\"center\">19<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">100<\/td><td class=\"has-text-align-center\" data-align=\"center\"><\/td><td class=\"has-text-align-center\" data-align=\"center\">2<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.1<\/td><td class=\"has-text-align-center\" data-align=\"center\">51<\/td><td class=\"has-text-align-center\" data-align=\"center\"><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Tableeau II : <\/strong>R\u00e9sultats de LLOQ et de MDL pour chaque compos\u00e9 semi-volatil<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>RMX-5Sil MS<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>RMX-5Sil MS<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>Colonne premium concurrente<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>Colonne premium concurrente<\/strong><\/td><\/tr><tr><td>Compos\u00e9<\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>LLOQ<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>MDL<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>LLOQ<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>MDL<\/strong><\/td><\/tr><tr><td>Acenaphthylene&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.42<\/td><td class=\"has-text-align-center\" data-align=\"center\">100<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.60<\/td><\/tr><tr><td>Phenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">2<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.45<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.27<\/td><\/tr><tr><td>4-Nitroaniline&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">2<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.22<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.43<\/td><\/tr><tr><td>2,4-Dimethylphenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.33<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.30<\/td><\/tr><tr><td>2-Nitrophenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.84<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.51<\/td><\/tr><tr><td>2-Methylphenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.84<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">2.37<\/td><\/tr><tr><td>Aniline&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.67<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.43<\/td><\/tr><tr><td>Diphenylamine&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.74<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.85<\/td><\/tr><tr><td>Benz[a]anthracene&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.29<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.49<\/td><\/tr><tr><td>2-Fluorobiphenyl&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.20<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.30<\/td><\/tr><tr><td>2-Methylnaphthalene&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.15<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.32<\/td><\/tr><tr><td>Benzo[ghi]perylene&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.39<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.08<\/td><\/tr><tr><td>Phenanthrene&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.19<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.15<\/td><\/tr><tr><td>4-Nitrophenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.38<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.31<\/td><\/tr><tr><td>3-Nitroaniline&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.40<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.33<\/td><\/tr><tr><td>3,3&#8242;-Dichlorobenzidine&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.37<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.76<\/td><\/tr><tr><td>N-Nitrosodimethylamine&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.63<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.53<\/td><\/tr><tr><td>Nitrobenzene-d5&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.13<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">.74<\/td><\/tr><tr><td>Acenaphthene&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.93<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.53<\/td><\/tr><tr><td>Benzo[b]fluoranthene&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.71<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.31<\/td><\/tr><tr><td>Benzo[k]fluoranthene&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.67<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">2.65<\/td><\/tr><tr><td>Benzo[a]pyrene&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.08<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">2.63<\/td><\/tr><tr><td>Fluorene&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.48<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.54<\/td><\/tr><tr><td>2,4,6-Trichlorophenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.40<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.16<\/td><\/tr><tr><td>2,6-Dichlorophenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">2<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.30<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.21<\/td><\/tr><tr><td>p-Terphenyl-d14&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">2<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.30<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.36<\/td><\/tr><tr><td>2,4,5-Trichlorophenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.92<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.33<\/td><\/tr><tr><td>2,3,4,6-Tetrachlorophenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.52<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.48<\/td><\/tr><tr><td>4-Chloro-3-methylphenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.06<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.21<\/td><\/tr><tr><td>Pentachlorophenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.18<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.93<\/td><\/tr><tr><td>4-Chloroaniline&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.55<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.32<\/td><\/tr><tr><td>o-Nitroaniline&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.49<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.36<\/td><\/tr><tr><td>1-Methylnaphthalene&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.13<\/td><td class=\"has-text-align-center\" data-align=\"center\">2<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.05<\/td><\/tr><tr><td>2-Chlorophenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.55<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.47<\/td><\/tr><tr><td>2,4,6-Tribromophenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.79<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">3.79<\/td><\/tr><tr><td>2,4-Dichlorophenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.32<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.41<\/td><\/tr><tr><td>2,4-Dinitrophenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.94<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">2.34<\/td><\/tr><tr><td>2-Fluorophenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.20<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.20<\/td><\/tr><tr><td>3- and 4-Methylphenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.59<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.69<\/td><\/tr><tr><td>Benzoic acid&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">100<\/td><td class=\"has-text-align-center\" data-align=\"center\">14.47<\/td><td class=\"has-text-align-center\" data-align=\"center\">100<\/td><td class=\"has-text-align-center\" data-align=\"center\">50.54<\/td><\/tr><tr><td>Phenol-d6&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.29<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.32<\/td><\/tr><tr><td>Benzidine&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">100<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.89<\/td><td class=\"has-text-align-center\" data-align=\"center\">100<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.97<\/td><\/tr><tr><td>Chrysene<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.30<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.23<\/td><\/tr><tr><td>Pyrene&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">103<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.10<\/td><\/tr><tr><td>Dibenz[a,h]anthracene&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.06<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">2.58<\/td><\/tr><tr><td>Indeno[1,2,3-cd]pyrene&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.59<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.81<\/td><\/tr><tr><td>Naphthalene<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.18<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.35<\/td><\/tr><tr><td>Fluoranthene<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.16<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.80<\/td><\/tr><tr><td>Anthracene<\/td><td class=\"has-text-align-center\" data-align=\"center\">5<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.86<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><td class=\"has-text-align-center\" data-align=\"center\">0.45<\/td><\/tr><tr><td>4,6-Dinitro-2-methylphenol&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">50<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.59<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">1.80<\/td><\/tr><tr><td>Dinoseb&nbsp;<\/td><td class=\"has-text-align-center\" data-align=\"center\">50<\/td><td class=\"has-text-align-center\" data-align=\"center\">2.23<\/td><td class=\"has-text-align-center\" data-align=\"center\">10<\/td><td class=\"has-text-align-center\" data-align=\"center\">3.39<\/td><\/tr><tr><td>Pyridine<\/td><td class=\"has-text-align-center\" data-align=\"center\">100<\/td><td class=\"has-text-align-center\" data-align=\"center\">7.73<\/td><td class=\"has-text-align-center\" data-align=\"center\">20<\/td><td class=\"has-text-align-center\" data-align=\"center\">11.39<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-custom-chromatogram-article-top\"><div class=\"chromatogram-article-placeholder\"><div class=\"figure-heading\"><strong>Figure 1 :<\/strong> Comparaison des MDL des compos\u00e9s semi-volatils sur une colonne RMX-5Sil MS par rapport \u00e0 une une colonne premium concurrente (les compos\u00e9s sont class\u00e9s par groupes acides, basiques et neutres).<\/div><div class='chromatogram-article-inner-full'><div class=\"chromatogram-article-inner\">\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"536\" src=\"https:\/\/discover.restek.com\/wp-content\/uploads\/figure-EVAN5255-01-1024x536.jpg\" alt=\"\" class=\"wp-image-63795\" title=\"-\" srcset=\"https:\/\/discover.restek.com\/wp-content\/uploads\/figure-EVAN5255-01-1024x536.jpg 1024w, https:\/\/discover.restek.com\/wp-content\/uploads\/figure-EVAN5255-01-300x157.jpg 300w, https:\/\/discover.restek.com\/wp-content\/uploads\/figure-EVAN5255-01-768x402.jpg 768w, https:\/\/discover.restek.com\/wp-content\/uploads\/figure-EVAN5255-01.jpg 1340w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n<\/div><\/div><\/div>\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-custom-chromatogram-article-top\"><div class=\"chromatogram-article-placeholder\"><div class=\"figure-heading\">Figure 2 : Comparaison des LLOQ des compos\u00e9s semi-volatils sur une colonne RMX-5Sil MS par rapport \u00e0 une colonne premium concurrente (les compos\u00e9s sont class\u00e9s par groupes acides, basiques et neutres).<\/div><div class='chromatogram-article-inner-full'><div class=\"chromatogram-article-inner\">\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"536\" src=\"https:\/\/discover.restek.com\/wp-content\/uploads\/figure-EVAN5255-02-1024x536.jpg\" alt=\"\" class=\"wp-image-63802\" title=\"-\" srcset=\"https:\/\/discover.restek.com\/wp-content\/uploads\/figure-EVAN5255-02-1024x536.jpg 1024w, https:\/\/discover.restek.com\/wp-content\/uploads\/figure-EVAN5255-02-300x157.jpg 300w, https:\/\/discover.restek.com\/wp-content\/uploads\/figure-EVAN5255-02-768x402.jpg 768w, https:\/\/discover.restek.com\/wp-content\/uploads\/figure-EVAN5255-02.jpg 1340w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n<\/div><\/div><\/div>\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Conclusion<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Un circuit d&#8217;\u00e9chantillon inerte permet d&#8217;atteindre des limites de d\u00e9tection plus basses pour l&#8217;analyse des semi-volatils, en tirant pleinement parti de la sensibilit\u00e9 \u00e9lev\u00e9e des instruments GC-MS\/MS. Les travaux pr\u00e9sent\u00e9s ici montrent que les colonnes RMX-5Sil MS, dot\u00e9e d&#8217;une inertie exceptionnelle, offrent une sensibilit\u00e9 sup\u00e9rieure \u00e0 celle d&#8217;une colonne premium concurrente. L&#8217;\u00e9valuation de la MDL et de la LLOQ a montr\u00e9 que des limites de d\u00e9tection et de quantification plus basses pouvaient \u00eatre obtenues pour une large gamme de compositions chimiques avec la colonne RMX-5Sil MS.<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/discover.restek.com\/fr\/rmx\/\"><img loading=\"lazy\" decoding=\"async\" width=\"2040\" height=\"1976\" src=\"https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-What-Makes-RMX-Better-HTML-1-FR.png\" alt=\"\" class=\"wp-image-79861\" title=\"-\" srcset=\"https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-What-Makes-RMX-Better-HTML-1-FR.png 2040w, https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-What-Makes-RMX-Better-HTML-1-FR-300x291.png 300w, https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-What-Makes-RMX-Better-HTML-1-FR-1024x992.png 1024w, https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-What-Makes-RMX-Better-HTML-1-FR-768x744.png 768w, https:\/\/discover.restek.com\/wp-content\/uploads\/RMX-Graphic-Ad-What-Makes-RMX-Better-HTML-1-FR-1536x1488.png 1536w\" sizes=\"auto, (max-width: 2040px) 100vw, 2040px\" \/><\/a><\/figure>\n<\/div>\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n        <div class=\"cpb\">\n            <h3 class=\"cpb-heading\">Produits Mentionn\u00e9s<\/h3>\n            <hr class=\"cpb-heading-underline\" \/>\n            <div class=\"cpb-list\">\n                                    <div class=\"cpb-item\">\n                        <div class=\"cpb-col cpb-col--left\">\n                            <a class=\"cpb-catalog\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/fr.restek.com\/p\/17323\">                                R\u00e9f. 17323                            <\/a>                        <\/div>\n                        <div class=\"cpb-col cpb-col--middle\">\n                            <div class=\"cpb-title\">Colonne capillaire GC RMX-5Sil MS, L 30 m, DI 0.25 mm, 0.25 \u00b5m<\/div>\n                        <\/div>\n                        <div class=\"cpb-col cpb-col--right\">\n                                                            <a class=\"cpb-view-btn\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/fr.restek.com\/p\/17323\">Voir le produit<\/a>\n                                                    <\/div>\n                    <\/div>\n                                    <div class=\"cpb-item\">\n                        <div class=\"cpb-col cpb-col--left\">\n                            <a class=\"cpb-catalog\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/23267\">                                R\u00e9f. 23267                            <\/a>                        <\/div>\n                        <div class=\"cpb-col cpb-col--middle\">\n                            <div class=\"cpb-title\">Insert Topaz Precision, 4.0\u00a0mm x 6.3 x 78.5, pour GC Thermo TRACE 1300\/1310, 1600\/1610 avec injecteur SSL, avec laine de quartz, d\u00e9sactivation Premium, lot de 5<\/div>\n                        <\/div>\n                        <div class=\"cpb-col cpb-col--right\">\n                                                            <a class=\"cpb-view-btn\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/23267\">Voir le produit<\/a>\n                                                    <\/div>\n                    <\/div>\n                                    <div class=\"cpb-item\">\n                        <div class=\"cpb-col cpb-col--left\">\n                            <a class=\"cpb-catalog\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/28500\">                                R\u00e9f. 28500                            <\/a>                        <\/div>\n                        <div class=\"cpb-col cpb-col--middle\">\n                            <div class=\"cpb-title\">D\u00e9tecteur \u00e9lectronique de fuites de gaz Restek<\/div>\n                        <\/div>\n                        <div class=\"cpb-col cpb-col--right\">\n                                                            <a class=\"cpb-view-btn\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/28500\">Voir le produit<\/a>\n                                                    <\/div>\n                    <\/div>\n                                    <div class=\"cpb-item\">\n                        <div class=\"cpb-col cpb-col--left\">\n                            <a class=\"cpb-catalog\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/31618\">                                R\u00e9f. 31618                            <\/a>                        <\/div>\n                        <div class=\"cpb-col cpb-col--middle\">\n                            <div class=\"cpb-title\">Solution \u00e9talon de calibration EPA 8270 n\u00b01, 2000 \u00b5g\/ml, chlorure de m\u00e9thyl\u00e8ne, ampoule de 1\u00a0ml<\/div>\n                        <\/div>\n                        <div class=\"cpb-col cpb-col--right\">\n                                                            <a class=\"cpb-view-btn\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/31618\">Voir le produit<\/a>\n                                                    <\/div>\n                    <\/div>\n                                    <div class=\"cpb-item\">\n                        <div class=\"cpb-col cpb-col--left\">\n                            <a class=\"cpb-catalog\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/31619\">                                R\u00e9f. 31619                            <\/a>                        <\/div>\n                        <div class=\"cpb-col cpb-col--middle\">\n                            <div class=\"cpb-title\">Solution \u00e9talon de calibration EPA 8270 n\u00b02, 2000\u00a0\u00b5g\/ml, chlorure de m\u00e9thyl\u00e8ne:m\u00e9thanol (85:15), ampoule de 1\u00a0ml<\/div>\n                        <\/div>\n                        <div class=\"cpb-col cpb-col--right\">\n                                                            <a class=\"cpb-view-btn\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/31619\">Voir le produit<\/a>\n                                                    <\/div>\n                    <\/div>\n                                    <div class=\"cpb-item\">\n                        <div class=\"cpb-col cpb-col--left\">\n                            <a class=\"cpb-catalog\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/31615\">                                R\u00e9f. 31615                            <\/a>                        <\/div>\n                        <div class=\"cpb-col cpb-col--middle\">\n                            <div class=\"cpb-title\">Solution \u00e9talon pour le r\u00e9glage des GC-MS, 1000\u00a0\u00b5g\/ml, chlorure de m\u00e9thyl\u00e8ne, ampoule de 1 ml<\/div>\n                        <\/div>\n                        <div class=\"cpb-col cpb-col--right\">\n                                                            <a class=\"cpb-view-btn\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/31615\">Voir le produit<\/a>\n                                                    <\/div>\n                    <\/div>\n                                    <div class=\"cpb-item\">\n                        <div class=\"cpb-col cpb-col--left\">\n                            <a class=\"cpb-catalog\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/31995\">                                R\u00e9f. 31995                            <\/a>                        <\/div>\n                        <div class=\"cpb-col cpb-col--middle\">\n                            <div class=\"cpb-title\">Solution \u00e9talon de calibration EPA 8270 n\u00b05, r\u00e9vis\u00e9e, 2000 \u00b5g\/ml, chlorure de m\u00e9thyl\u00e8ne, ampoule de 1\u00a0ml<\/div>\n                        <\/div>\n                        <div class=\"cpb-col cpb-col--right\">\n                                                            <a class=\"cpb-view-btn\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/31995\">Voir le produit<\/a>\n                                                    <\/div>\n                    <\/div>\n                                    <div class=\"cpb-item\">\n                        <div class=\"cpb-col cpb-col--left\">\n                            <a class=\"cpb-catalog\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/31025\">                                R\u00e9f. 31025                            <\/a>                        <\/div>\n                        <div class=\"cpb-col cpb-col--middle\">\n                            <div class=\"cpb-title\">Solution \u00e9talon de compos\u00e9s de substitution acides (4\/89 SOW), 2000 \u00b5g\/ml, m\u00e9thanol, ampoule de 1 ml<\/div>\n                        <\/div>\n                        <div class=\"cpb-col cpb-col--right\">\n                                                            <a class=\"cpb-view-btn\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/31025\">Voir le produit<\/a>\n                                                    <\/div>\n                    <\/div>\n                                    <div class=\"cpb-item\">\n                        <div class=\"cpb-col cpb-col--left\">\n                            <a class=\"cpb-catalog\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/31024\">                                R\u00e9f. 31024                            <\/a>                        <\/div>\n                        <div class=\"cpb-col cpb-col--middle\">\n                            <div class=\"cpb-title\">Solution \u00e9talon de compos\u00e9s de substitution basiques ou neutres (4\/89 SOW), 1000 \u00b5g\/ml, chlorure de m\u00e9thyl\u00e8ne, ampoule de 1 ml<\/div>\n                        <\/div>\n                        <div class=\"cpb-col cpb-col--right\">\n                                                            <a class=\"cpb-view-btn\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/31024\">Voir le produit<\/a>\n                                                    <\/div>\n                    <\/div>\n                                    <div class=\"cpb-item\">\n                        <div class=\"cpb-col cpb-col--left\">\n                            <a class=\"cpb-catalog\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/31886\">                                R\u00e9f. 31886                            <\/a>                        <\/div>\n                        <div class=\"cpb-col cpb-col--middle\">\n                            <div class=\"cpb-title\">M\u00e9lange d\u2019\u00e9talons internes de SV r\u00e9vis\u00e9, 4000 \u00b5g\/ml, chlorure de m\u00e9thyl\u00e8ne, ampoule de 1\u00a0ml<\/div>\n                        <\/div>\n                        <div class=\"cpb-col cpb-col--right\">\n                                                            <a class=\"cpb-view-btn\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.restek.com\/p\/31886\">Voir le produit<\/a>\n                                                    <\/div>\n                    <\/div>\n                            <\/div>\n        <\/div>\n        \n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00c9l\u00e9ments cl\u00e9s R\u00e9sum\u00e9 Cette \u00e9tude examine l&#8217;impact de la d\u00e9sactivation de colonne GC sur l&#8217;abaissement des limites de d\u00e9tection pour l&#8217;analyse des compos\u00e9s semi-volatils par GC-MS\/MS. Les MDL et LLOQ obtenues avec une colonne RMX-5Sil MS se sont r\u00e9v\u00e9l\u00e9es nettement plus basses pour environ deux tiers des compos\u00e9s test\u00e9s, par rapport \u00e0 une colonne premium&#8230;<\/p>\n","protected":false},"author":62,"featured_media":62681,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"default","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"footnotes":"","_ppma_block_editor_authors":""},"categories":[462],"tags":[2743],"industries-application":[2208],"post-badge":[],"resource-type":[],"product-library":[],"resource-technique":[],"ppma_author":[454,441,2657,452],"class_list":["post-105417","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles-fr","tag-rmx-resources","industries-application-environnement"],"acf":[],"taxonomy_info":{"category":[{"value":462,"label":"Articles"}],"post_tag":[{"value":2743,"label":"Ressources RMX"}],"industries-application":[{"value":2208,"label":"Environnement"}]},"featured_image_src_large":["https:\/\/discover.restek.com\/wp-content\/uploads\/feature-EVAN5255-1024x536.jpg",1024,536,true],"author_info":{"display_name":"Virginie Bonnamy","author_link":"https:\/\/discover.restek.com\/fr\/author\/virginie-bonnamy\/"},"comment_info":0,"category_info":[{"term_id":462,"name":"Articles","slug":"articles-fr","term_group":0,"term_taxonomy_id":462,"taxonomy":"category","description":"","parent":0,"count":511,"filter":"raw","cat_ID":462,"category_count":511,"category_description":"","cat_name":"Articles","category_nicename":"articles-fr","category_parent":0}],"tag_info":[{"term_id":2743,"name":"Ressources RMX","slug":"rmx-resources","term_group":0,"term_taxonomy_id":2743,"taxonomy":"post_tag","description":"Explorez les ressources RMX","parent":0,"count":23,"filter":"raw"}],"authors":[{"term_id":454,"user_id":34,"is_guest":0,"slug":"erica-pack-phd","display_name":"Erica Pack, PhD","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-pack-erica.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-pack-erica.jpg"},"author_category":"1","first_name":"Erica","last_name":"Pack","user_url":"https:\/\/www.linkedin.com\/in\/ericapack\/","job_title":"Senior Scientist, GC Applied","description":"Erica is an interdisciplinary GC applications and technologies scientist at Restek. She obtained her bachelor's degree in forensic biology from The Pennsylvania State University, and her doctorate from Virginia Tech in plant pathology, physiology, and weed science. Since joining Restek in 2021, she has worked with a wide variety of GC columns, including fused silica, MXT, PLOT, and packed columns as well as accessories, such as liners, valves, and methanizers."},{"term_id":441,"user_id":21,"is_guest":0,"slug":"chris-english","display_name":"Chris English","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-english-chris.png","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-english-chris.png"},"author_category":"1","first_name":"Chris","last_name":"English","user_url":"https:\/\/www.linkedin.com\/in\/chris-english-28214912\/","job_title":"Sr. R&D Manager","description":"Since 2004, Chris has managed a team of chemists in Restek's innovations laboratory who perform new product testing, method development, and applications work. Before taking the reins of our lab, he spent seven years as an environmental chemist and was critical to the development of Restek\u2019s current line of volatile GC columns. Prior to joining Restek, he operated a variety of gas chromatographic detectors conducting method development and sample analysis. Chris holds a BS in environmental science from Saint Michael's College."},{"term_id":2657,"user_id":70,"is_guest":0,"slug":"ramkumar-dhandapani-phd","display_name":"Ramkumar Dhandapani, PhD","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/Dhandapani_Ramkumar_Profile.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/Dhandapani_Ramkumar_Profile.jpg"},"author_category":"1","first_name":"Ramkumar","last_name":"Dhandapani","user_url":"https:\/\/www.linkedin.com\/in\/dr-ramkumar-dhandapani-b9012424\/?skipRedirect=true&enhance=null","job_title":"Director of Product Management","description":"Dr. Ramkumar Dhandapani\u00a0is a seasoned analytical chemist with over\u00a023 years of experience\u00a0in the chromatography industry and a Ph.D. in analytical chemistry. During his career, he has specialized in method development, validation, and the troubleshooting of chromatography methods. He has developed numerous regulatory-compliant methods across diverse sectors, including\u00a0environmental analysis, food quality and safety, pharmaceutical, fuels, and chemical industries. Currently, Dr. Dhandapani is the Director of Product Management at Restek, he is keen on innovation in chromatography and scaling breakthrough innovations\u00a0to market as commercial products."},{"term_id":452,"user_id":32,"is_guest":0,"slug":"colton-myers","display_name":"Colton Myers","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-myers-colton.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-myers-colton.jpg"},"author_category":"1","first_name":"Colton","last_name":"Myers","user_url":"https:\/\/www.linkedin.com\/in\/myerscolton\/","job_title":"Product Manager - New Product Development","description":"Colton Myers is a Product Manager for GC columns at Restek Corporation with over 10 years of experience in research and development. He specializes in driving new GC column technologies from concept to market, combining deep technical expertise with a strong focus on innovation and commercialization. Colton holds a BS in chemistry from Juniata College and a Master of Management in Corporate Innovation and Entrepreneurship from Penn State University."}],"_links":{"self":[{"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/posts\/105417","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/users\/62"}],"replies":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/comments?post=105417"}],"version-history":[{"count":4,"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/posts\/105417\/revisions"}],"predecessor-version":[{"id":105426,"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/posts\/105417\/revisions\/105426"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/media\/62681"}],"wp:attachment":[{"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/media?parent=105417"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/categories?post=105417"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/tags?post=105417"},{"taxonomy":"industries-application","embeddable":true,"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/industries-application?post=105417"},{"taxonomy":"post-badge","embeddable":true,"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/post-badge?post=105417"},{"taxonomy":"resource-type","embeddable":true,"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/resource-type?post=105417"},{"taxonomy":"product-library","embeddable":true,"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/product-library?post=105417"},{"taxonomy":"resource-technique","embeddable":true,"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/resource-technique?post=105417"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/discover.restek.com\/fr\/wp-json\/wp\/v2\/ppma_author?post=105417"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}