You can use Ultra or Roc 5 µm guard cartridges for fully porous particle (FPP) columns with a particle size of 3 µm or greater, provided the packing material is very similar. For “core-shell” or superficially porous particles (SPP), a Raptor 2.7 µm or 5 µm guard can be used for similar phases and particle sizes. For FPP or SPP particles less than 2 µm, a Raptor UHPLC guard column can be used for similar phases. Make sure to use the appropriate Roc, Trident, or Raptor guard holder. Some of the column stationary phases/packing materials that are similar to ours are listed in this chart for easy reference.
In some cases, the stationary phase may be so unique that you might need to purchase guard cartridge supplies from the same vendor in order to obtain the best results. Feel free to call us if you have questions about this.
We recommend using only Restek guard cartridge holders with Restek guard cartridges in order to ensure a proper fit.
