Author(s): Jana Hinz1,3, Tessema F. Mekonnen2, Jonas Bergrath1, Savanna Sewell1, Yannic Schneck1, Michaela Wirtz1, Ursula Telgheder3
1. Department of Natural Sciences, Bonn-Rhein-Sieg University of Applied Sciences, Heisenbergstraße 16, Rheinbach 53359, Germany
2. Max Planck Institute for Chemical Energy Conversion, Stiftstr. 34-36, 45470, Germany
3. Faculty of Chemistry, University of Duisburg-Essen, Instrumental Analytical Chemistry, Universitätsstraße 5, Essen 45141, Germany
Published By: Journal of Chromatography Open
Issue: Volume 4
Year of Publication: 2023
Link: https://doi.org/10.1016/j.jcoa.2023.100102
Abstract: This study aims to analyse nine nitrosamines relevant in the field of occupational safety using a gas chromatography-drift tube ion mobility spectrometry (GC-DT-IMS) system. To do this, single nitrosamine standards as well as a standard mix, each at 0.1 g/L, were introduced via liquid injection. A GC-DT-IMS method capable of separating the nitrosamine signals according to retention time (first dimension) and drift time (second dimension) in 10 min was developed. The system shows excellent selectivity as each nitrosamine gives two signals pertaining to monomer and dimer in the second dimension. For the first time, reduced ion mobility values for nitrosamines were determined, ranging from 1.18 to 2.03 cm2s-1V-1. The high selectivity of the GC-DT-IMS method could provide a definite advantage for monitoring nitrosamines in different manufacturing industries and consumer products.
Acknowledgment(s): The analysis outlined in this application note featured a Rtx-200 GC capillary column (cat.# 15023).
