One of the most common questions I am asked by customers is “Why is my peak shape so poor?” Another is “I do not see a peak for my compound, what should I do?” Sometimes they are developing a new…

Bile acids are a group of steroidal acids with carboxyl and hydroxyl groups on the side. They are the major metabolic products of cholesterol. Bile acids play important roles as biomarkers for early diagnosis and therapeutic monitoring of many diseases,…

My first blog here at Restek was a demonstration of how increasing the source temperature could improve the raw response of 2,4-dinitrophenol while maintaining the relative response. Four years later I’m here with the promised follow-up on the elevated source…

Recently one of the designers of the Super-Clean Gas Filters spent some time with technical service and we were able to ask him a few common questions we get asked by customers. I thought I would share this information with…

Recently I came across a situation where I wanted to make a series of constant flow GC-FID runs, during which, the inlet pressure would increase from 2 to 6 PSI over the temperature program. I also wanted to use split…

Peak Capacity in capillary gas chromatography is different than sample loading capacity, which is something I’ve posted on multiple times recently in ChromaBLOGraphy. Peak capacity is simply the number of theoretical peaks that can “fit” inside a chromatogram under some…

You’re ready to install a column into your GC and realize you do not have ferrules to do the job. But which ferrule do you choose? The parameters to consider when choosing the correct ferrule are instrument make and model,…

The first time I was asked by a customer about how to convert % by weight of one of our FAME reference standards to µg/mL, I needed to ask for some help. Because we (tech service) occasionally get asked this…