{"id":4115,"date":"2025-08-01T17:56:44","date_gmt":"2025-08-01T17:56:44","guid":{"rendered":"https:\/\/discover.restek.com\/?p=4115"},"modified":"2025-12-08T23:13:48","modified_gmt":"2025-12-08T23:13:48","slug":"do-i-need-to-passivate-my-hplc","status":"publish","type":"post","link":"https:\/\/discover.restek.com\/it\/faq\/gnot5107\/do-i-need-to-passivate-my-hplc","title":{"rendered":"Do I need to passivate my HPLC?"},"content":{"rendered":"\n<p>Possibly. Unless you are using an inert HPLC system, the metal in the flow path from the injector to the column may have some impact on certain metal-sensitive compounds. We have\u00a0a recommended procedure\u00a0for injecting a passivation solution through the system that can help.<\/p>\n\n\n\n<div data-wp-interactive=\"core\/file\" class=\"wp-block-file\"><object data-wp-bind--hidden=\"!state.hasPdfPreview\" hidden class=\"wp-block-file__embed\" data=\"https:\/\/discover.restek.com\/wp-content\/uploads\/480-01-001.pdf\" type=\"application\/pdf\" style=\"width:100%;height:600px\" aria-label=\"Embed of 480-01-001.\"><\/object><a id=\"wp-block-file--media-952bb7b7-ff06-4b0b-bc35-49c49d39e76a\" href=\"https:\/\/discover.restek.com\/wp-content\/uploads\/480-01-001.pdf\">480-01-001<\/a><a href=\"https:\/\/discover.restek.com\/wp-content\/uploads\/480-01-001.pdf\" class=\"wp-block-file__button wp-element-button\" download aria-describedby=\"wp-block-file--media-952bb7b7-ff06-4b0b-bc35-49c49d39e76a\">Download<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Possibly. Unless you are using an inert HPLC system, the metal in the flow path from the injector to the column may have some impact on certain metal-sensitive compounds. We have\u00a0a recommended procedure\u00a0for injecting a passivation solution through the system that can help.<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"footnotes":""},"categories":[23],"tags":[2682,2704],"industries-application":[],"post-badge":[],"resource-type":[],"product-library":[],"resource-technique":[],"hf_cat_post":[625],"ppma_author":[414],"class_list":["post-4115","post","type-post","status-publish","format-standard","hentry","category-faq","tag-faq-hplc-and-uhplc","tag-faq-inert-lc-columns"],"acf":[],"taxonomy_info":{"category":[{"value":23,"label":"FAQ"}],"post_tag":[{"value":2682,"label":"FAQ: HPLC and UHPLC"},{"value":2704,"label":"FAQ: Inert LC Columns"}]},"featured_image_src_large":false,"author_info":{"display_name":"Restek Corporation","author_link":"https:\/\/discover.restek.com\/it\/author\/restek-corporation\/"},"comment_info":0,"category_info":[{"term_id":23,"name":"FAQ","slug":"faq","term_group":0,"term_taxonomy_id":23,"taxonomy":"category","description":"","parent":0,"count":271,"filter":"raw","cat_ID":23,"category_count":271,"category_description":"","cat_name":"FAQ","category_nicename":"faq","category_parent":0}],"tag_info":[{"term_id":2682,"name":"FAQ: HPLC and UHPLC","slug":"faq-hplc-and-uhplc","term_group":0,"term_taxonomy_id":2682,"taxonomy":"post_tag","description":"Browse frequently asked questions for HPLC and UHPLC products.","parent":0,"count":61,"filter":"raw"},{"term_id":2704,"name":"FAQ: Inert LC Columns","slug":"faq-inert-lc-columns","term_group":0,"term_taxonomy_id":2704,"taxonomy":"post_tag","description":"Browse frequently asked questions for inert LC columns.","parent":0,"count":16,"filter":"raw"}],"authors":[{"term_id":414,"user_id":11,"is_guest":0,"slug":"restek-corporation","display_name":"Restek Corporation","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/Restek_Favicon_300x300.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/Restek_Favicon_300x300.jpg"},"0":null,"1":"","2":"","3":"","4":"","5":"","6":"","7":"","8":""}],"_links":{"self":[{"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/posts\/4115","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/comments?post=4115"}],"version-history":[{"count":3,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/posts\/4115\/revisions"}],"predecessor-version":[{"id":70438,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/posts\/4115\/revisions\/70438"}],"wp:attachment":[{"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/media?parent=4115"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/categories?post=4115"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/tags?post=4115"},{"taxonomy":"industries-application","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/industries-application?post=4115"},{"taxonomy":"post-badge","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/post-badge?post=4115"},{"taxonomy":"resource-type","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/resource-type?post=4115"},{"taxonomy":"product-library","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/product-library?post=4115"},{"taxonomy":"resource-technique","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/resource-technique?post=4115"},{"taxonomy":"hf_cat_post","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/hf_cat_post?post=4115"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/ppma_author?post=4115"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}