{"id":43782,"date":"2025-10-03T21:40:03","date_gmt":"2025-10-03T21:40:03","guid":{"rendered":"https:\/\/discover.restek.com\/uncategorized\/investigation-of-operational-fundamentals-for-vacuum-assisted-headspace-high-capacity-solid-phase-microextraction-and-gas-chromatographic-analysis-of-semivolatile-compounds-from-a-model-solid-sample\/"},"modified":"2026-07-29T20:30:56","modified_gmt":"2026-07-29T20:30:56","slug":"investigation-of-operational-fundamentals-for-vacuum-assisted-headspace-high-capacity-solid-phase-microextraction-and-gas-chromatographic-analysis-of-semivolatile-compounds-from-a-model-solid-sample","status":"publish","type":"post","link":"https:\/\/discover.restek.com\/it\/articles\/gnot4272\/investigation-of-operational-fundamentals-for-vacuum-assisted-headspace-high-capacity-solid-phase-microextraction-and-gas-chromatographic-analysis-of-semivolatile-compounds-from-a-model-solid-sample","title":{"rendered":"Investigation of operational fundamentals for vacuum-assisted headspace high-capacity solid-phase microextraction and gas chromatographic analysis of semivolatile compounds from a model solid sample"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Author(s):<\/strong> Shannon L. Thomas<sup>1<\/sup>, Colton Myers<sup>2<\/sup>, Jason S. Herrington<sup>2<\/sup>, Kevin A. Schug<sup>1<\/sup><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Department of Chemistry and Biochemistry, The University of Texas at Arlington, Arlington, Texas, USA<\/li>\n\n\n\n<li>Restek Corporation, Bellefonte, Pennsylvania, USA<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Published By:<\/strong> Journal of Separation Science<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Issue:<\/strong> Volume 47, Issue 8<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Year of Publication:<\/strong> 2024<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Link:<\/strong> <a href=\"https:\/\/doi.org\/10.1002\/jssc.202300779\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1002\/jssc.202300779<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Abstract:<\/strong> Vacuum-assisted headspace solid-phase microextraction (Vac-HS-SPME) is a technique used to enhance SPME sampling of semi-volatile organic compounds. Here, it was combined with a high-capacity SPME Arrow, which features a larger volume of extraction phase and a more rugged configuration than traditional extraction fibers. An in-depth assessment of the critical parameters was conducted to achieve optimal extraction of representative compounds from a model solid sample matrix (Ottawa sand). Operational fundamentals investigated included the types of seals needed to create a leak-free environment under vacuum conditions; the magnitude of the vacuum applied and time needed to activate the Vac kinetics; order of sample vial preparation methods (VPMs); and other standard variables associated with extract analysis by gas chromatography-mass spectrometry. When exploring the limits of sample VPMs, results indicated an ideal workflow requires the solid sample to be spiked before sealing the vial, allow the sample to rest overnight, then apply vacuum at a pressure of -677 mbar (out of -789 mbar maximum possible vacuum with pump and compressor used), exerted on the vial for 90 s. This work provides the necessary workflow for the optimization of Vac-HS-SPME sampling of analytes from solid matrices.<\/p>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>An in-depth assessment of the critical parameters for vacuum-assisted headspace solid-phase microextraction (Vac-HS-SPME) using high-capacity SPME Arrows was conducted to achieve optimal extraction of representative compounds from a model solid sample matrix. This work provides the necessary workflow for the optimization of Vac-HS-SPME sampling of analytes from solid matrices.<\/p>\n","protected":false},"author":32,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"footnotes":""},"categories":[7],"tags":[],"industries-application":[],"post-badge":[],"resource-type":[568],"product-library":[],"resource-technique":[],"ppma_author":[747,452,445,707],"class_list":["post-43782","post","type-post","status-publish","format-standard","hentry","category-articles","resource-type-third-party-peer-reviewed-publications"],"acf":[],"taxonomy_info":{"category":[{"value":7,"label":"Articles"}],"resource-type":[{"value":568,"label":"Third-Party &amp; Peer Reviewed Publications"}]},"featured_image_src_large":false,"author_info":{"display_name":"Colton Myers","author_link":"https:\/\/discover.restek.com\/it\/author\/colton-myers\/"},"comment_info":0,"category_info":[{"term_id":7,"name":"Articles","slug":"articles","term_group":0,"term_taxonomy_id":7,"taxonomy":"category","description":"","parent":0,"count":464,"filter":"raw","cat_ID":7,"category_count":464,"category_description":"","cat_name":"Articles","category_nicename":"articles","category_parent":0}],"tag_info":false,"authors":[{"term_id":747,"user_id":0,"is_guest":1,"slug":"shannon-l-thomas","display_name":"Shannon L. Thomas","avatar_url":"https:\/\/secure.gravatar.com\/avatar\/?s=96&d=mm&r=g","author_category":"1","first_name":"Shannon L.","last_name":"Thomas","user_url":"","job_title":"","description":"Department of Chemistry and Biochemistry, The University of Texas at Arlington, Arlington, Texas, USA"},{"term_id":452,"user_id":32,"is_guest":0,"slug":"colton-myers","display_name":"Colton Myers","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-myers-colton.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-myers-colton.jpg"},"author_category":"1","first_name":"Colton","last_name":"Myers","user_url":"https:\/\/www.linkedin.com\/in\/myerscolton\/","job_title":"Product Manager - New Product Development","description":"Colton Myers is a Product Manager for GC columns at Restek Corporation with over 10 years of experience in research and development. He specializes in driving new GC column technologies from concept to market, combining deep technical expertise with a strong focus on innovation and commercialization. Colton holds a BS in chemistry from Juniata College and a Master of Management in Corporate Innovation and Entrepreneurship from Penn State University."},{"term_id":445,"user_id":25,"is_guest":0,"slug":"jason-s-herrington-phd","display_name":"Jason S. Herrington, PhD","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-herrington-jason.png","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-herrington-jason.png"},"author_category":"1","first_name":"Jason","last_name":"Herrington","user_url":"","job_title":"","description":"Jason joined Restek in 2011 after spending over 10 years in environmental analysis, most notably as a postdoctoral research fellow with the U.S. EPA focusing on the development of techniques for organic speciation of ambient gas-phase and particulate air toxics. He has a BS in environmental sciences from Rutgers University and a PhD in exposure science from The University of Medicine and Dentistry of New Jersey. His wide-ranging work has been published in over a dozen peer-reviewed manuscripts and presented around the world. As a senior scientist with Restek, Jason is heavily involved with developing new air products and applications."},{"term_id":707,"user_id":0,"is_guest":1,"slug":"kevin-a-schug","display_name":"Kevin A. Schug","avatar_url":"https:\/\/secure.gravatar.com\/avatar\/?s=96&d=mm&r=g","author_category":"1","first_name":"Kevin A.","last_name":"Schug","user_url":"","job_title":"","description":"Department of Chemistry and Biochemistry, The University of Texas at Arlington, Arlington, Texas, USA"}],"_links":{"self":[{"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/posts\/43782","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/users\/32"}],"replies":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/comments?post=43782"}],"version-history":[{"count":2,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/posts\/43782\/revisions"}],"predecessor-version":[{"id":62260,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/posts\/43782\/revisions\/62260"}],"wp:attachment":[{"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/media?parent=43782"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/categories?post=43782"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/tags?post=43782"},{"taxonomy":"industries-application","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/industries-application?post=43782"},{"taxonomy":"post-badge","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/post-badge?post=43782"},{"taxonomy":"resource-type","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/resource-type?post=43782"},{"taxonomy":"product-library","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/product-library?post=43782"},{"taxonomy":"resource-technique","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/resource-technique?post=43782"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/ppma_author?post=43782"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}