{"id":90554,"date":"2026-03-20T19:34:35","date_gmt":"2026-03-20T19:34:35","guid":{"rendered":"https:\/\/discover.restek.com\/?p=90554"},"modified":"2026-07-20T20:36:37","modified_gmt":"2026-07-20T20:36:37","slug":"optimizing-injection-port-conditions-for-the-analysis-of-semivolatile-organics","status":"publish","type":"post","link":"https:\/\/discover.restek.com\/it\/posters-presentations\/gnot5656\/optimizing-injection-port-conditions-for-the-analysis-of-semivolatile-organics","title":{"rendered":"Optimizing Injection Port Conditions for the Analysis of Semivolatile Organics"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Split and splitless injections introduce the sample into a heated injection port as a liquid where it is rapidly and completely vaporized along with the analytes in the sample. The vaporized sample condenses at the head of the column along with the solvent. In split injection mode only a small amount of the vaporized sample is transferred onto the head of the column, the remainder of the sample and solvent is removed via the split vent line. The use of split injection minimizes analyte breakdown since compounds spend less time in the hot injection port, however, loss in sensitivity is observed since much of the sample exists the split vent line. In splitless injection the split valve is closed long enough to allow most of the vaporized sample and solvent in the injection port liner to be transferred to the analytical column which can take anywhere between 30 and 90 seconds. This work will demonstrate optimized conditions for a broad range of semivolatile compounds using methylene chloride as a solvent and feature the benefits of split injection for the analysis of semivolatiles.<\/p>\n\n\n\n<div data-wp-interactive=\"core\/file\" class=\"wp-block-file\"><object data-wp-bind--hidden=\"!state.hasPdfPreview\" hidden class=\"wp-block-file__embed\" data=\"https:\/\/discover.restek.com\/wp-content\/uploads\/poster-pittcon-2026-RMX-liner.pdf\" type=\"application\/pdf\" style=\"width:100%;height:600px\" aria-label=\"Embed of poster-pittcon-2026-RMX-liner.\"><\/object><a id=\"wp-block-file--media-b0f59a47-3027-45dc-ab90-728137ae10dd\" href=\"https:\/\/discover.restek.com\/wp-content\/uploads\/poster-pittcon-2026-RMX-liner.pdf\">poster-pittcon-2026-RMX-liner<\/a><a href=\"https:\/\/discover.restek.com\/wp-content\/uploads\/poster-pittcon-2026-RMX-liner.pdf\" class=\"wp-block-file__button wp-element-button\" download aria-describedby=\"wp-block-file--media-b0f59a47-3027-45dc-ab90-728137ae10dd\">Download<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Split and splitless injections introduce the sample into a heated injection port as a liquid where it is rapidly and completely vaporized along with the analytes in the sample. The vaporized sample condenses at the head of the column along with the solvent.<\/p>\n","protected":false},"author":70,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"footnotes":""},"categories":[12],"tags":[],"industries-application":[],"post-badge":[],"resource-type":[],"product-library":[],"resource-technique":[],"ppma_author":[2657,452,765,454,439,441],"class_list":["post-90554","post","type-post","status-publish","format-standard","hentry","category-posters-presentations"],"acf":[],"taxonomy_info":{"category":[{"value":12,"label":"Posters &amp; Presentations"}]},"featured_image_src_large":false,"author_info":{"display_name":"Ramkumar Dhandapani, PhD","author_link":"https:\/\/discover.restek.com\/it\/author\/ramkumar-dhandapani-phd\/"},"comment_info":0,"category_info":[{"term_id":12,"name":"Posters &amp; Presentations","slug":"posters-presentations","term_group":0,"term_taxonomy_id":12,"taxonomy":"category","description":"","parent":0,"count":118,"filter":"raw","cat_ID":12,"category_count":118,"category_description":"","cat_name":"Posters &amp; Presentations","category_nicename":"posters-presentations","category_parent":0}],"tag_info":false,"authors":[{"term_id":2657,"user_id":70,"is_guest":0,"slug":"ramkumar-dhandapani-phd","display_name":"Ramkumar Dhandapani, PhD","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/Dhandapani_Ramkumar_Profile.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/Dhandapani_Ramkumar_Profile.jpg"},"author_category":"1","first_name":"Ramkumar","last_name":"Dhandapani","user_url":"","job_title":"Director of Product Management","description":"Dr. Ramkumar Dhandapani\u00a0is a seasoned analytical chemist with over\u00a023 years of experience\u00a0in the chromatography industry and a Ph.D. in analytical chemistry. During his career, he has specialized in method development, validation, and the troubleshooting of chromatography methods. He has developed numerous regulatory-compliant methods across diverse sectors, including\u00a0environmental analysis, food quality and safety, pharmaceutical, fuels, and chemical industries. Currently, Dr. Dhandapani is the Director of Product Management at Restek, he is keen on innovation in chromatography and scaling breakthrough innovations\u00a0to market as commercial products."},{"term_id":452,"user_id":32,"is_guest":0,"slug":"colton-myers","display_name":"Colton Myers","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-myers-colton.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-myers-colton.jpg"},"author_category":"1","first_name":"Colton","last_name":"Myers","user_url":"https:\/\/www.linkedin.com\/in\/myerscolton\/","job_title":"Product Manager - New Product Development","description":"Colton Myers is a Product Manager for GC columns at Restek Corporation with over 10 years of experience in research and development. He specializes in driving new GC column technologies from concept to market, combining deep technical expertise with a strong focus on innovation and commercialization. Colton holds a BS in chemistry from Juniata College and a Master of Management in Corporate Innovation and Entrepreneurship from Penn State University."},{"term_id":765,"user_id":0,"is_guest":1,"slug":"victoria-r-zeger","display_name":"Victoria R. Zeger","avatar_url":"https:\/\/secure.gravatar.com\/avatar\/?s=96&d=mm&r=g","author_category":"1","first_name":"Victoria R.","last_name":"Zeger","user_url":"","job_title":"","description":"Department of Chemistry, Iowa State University, Ames, IA 50011, USA"},{"term_id":454,"user_id":34,"is_guest":0,"slug":"erica-pack-phd","display_name":"Erica Pack, PhD","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-pack-erica.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-pack-erica.jpg"},"author_category":"1","first_name":"Erica","last_name":"Pack","user_url":"https:\/\/www.linkedin.com\/in\/ericapack\/","job_title":"","description":"Erica is an interdisciplinary GC applications and technologies scientist at Restek. She obtained her bachelor's degree in forensic biology from The Pennsylvania State University, and her doctorate from Virginia Tech in plant pathology, physiology, and weed science. Since joining Restek in 2021, she has worked with a wide variety of GC columns, including fused silica, MXT, PLOT, and packed columns as well as accessories, such as liners, valves, and methanizers."},{"term_id":439,"user_id":19,"is_guest":0,"slug":"jaap-de-zeeuw","display_name":"Jaap de Zeeuw","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-de-zeeuw-jaap.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-de-zeeuw-jaap.jpg"},"author_category":"1","first_name":"Jaap","last_name":"de Zeeuw","user_url":"","job_title":"","description":"Jaap is a world-renowned chromatographer with over 40 years of experience, including 15 years with Restek and 27 years with Varian\/Chrompack prior to joining Restek. Throughout his career, Jaap has focused the chromatographic challenges of industrial analysis. For his 1979 graduation from The Institute for Higher Education, where he specialized in chemistry, Jaap authored a paper titled \"The Challenge of Coating Flexible Fused Silica Capillary Columns\" and has since distinguished himself as an authority on the subject. Jaap has been directly involved with the creation of numerous chemically bonded columns, including the first bonded PEG column and the stabilized PLOT columns widely used in the petrochemical arena. He has also helped develop new techniques, such as fast GC-MS using vacuum GC technology (low-pressure GC or LPGC). Over his innovative career, he has filed several patents for his work. Based out of the Netherlands, Jaap is extensively published and regularly travels internationally to share his knowledge. After retiring from Restek, Jaap founded CreaVisions, where he works as a GC Consultant and teaches master classes on key GC topics as well as on creativity in science."},{"term_id":441,"user_id":21,"is_guest":0,"slug":"chris-english","display_name":"Chris English","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-english-chris.png","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-english-chris.png"},"author_category":"1","first_name":"Chris","last_name":"English","user_url":"https:\/\/www.linkedin.com\/in\/chris-english-28214912\/","job_title":"Sr. R&D Manager","description":"Since 2004, Chris has managed a team of chemists in Restek's innovations laboratory who perform new product testing, method development, and applications work. Before taking the reins of our lab, he spent seven years as an environmental chemist and was critical to the development of Restek\u2019s current line of volatile GC columns. Prior to joining Restek, he operated a variety of gas chromatographic detectors conducting method development and sample analysis. Chris holds a BS in environmental science from Saint Michael's College."}],"_links":{"self":[{"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/posts\/90554","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/users\/70"}],"replies":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/comments?post=90554"}],"version-history":[{"count":2,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/posts\/90554\/revisions"}],"predecessor-version":[{"id":90557,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/posts\/90554\/revisions\/90557"}],"wp:attachment":[{"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/media?parent=90554"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/categories?post=90554"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/tags?post=90554"},{"taxonomy":"industries-application","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/industries-application?post=90554"},{"taxonomy":"post-badge","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/post-badge?post=90554"},{"taxonomy":"resource-type","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/resource-type?post=90554"},{"taxonomy":"product-library","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/product-library?post=90554"},{"taxonomy":"resource-technique","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/resource-technique?post=90554"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/discover.restek.com\/it\/wp-json\/wp\/v2\/ppma_author?post=90554"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}