FAQ

Which syringe filters are compatible with my solvents or matrix?

30 Jul 2025

Please use the Syringe Filter Membrane Selection Guide (below) and the Syringe Filter Solvent Compatibility Chart. Best practices dictate verifying compatibility prior to use.

Syringe Filter Membrane Selection Guide

MembranePropertiesApplicationsIncompatible with
Cellulose Acetatehydrophilicaqueous solutionsorganic solvents
Nylonhydrophilic, low protein bindingbases, HPLC solvents, alcohols, aromatic hydrocarbonsacids, aggressive halogenated hydrocarbons, proteins
PEShydrophilic, low protein binding, fast flow ratesfiltration of butters & culture media
PTFEhydrophobicorganic solvents, acids, alcohols, bases, aromaticsaqueous samples without pre-wetting (to avoid high back pressure)
PVDFhydrophilic, low protein bindingalcohols, biomoleculesbases, esters, ethers, ketones
Polypropylene (PP)hydrophilic, low protein binding, high solvent resistance, good thermal compatibilitybiological samples, solvents, aqueous solutionsstrong oxidizing acids, halogenated and aromatic hydrocarbons

Hydrophilic applications: cellulose acetate, nylon, PES, PVDF, PP
Hydrophobic applications: PTFE

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