{"id":3268,"date":"2025-07-31T12:57:24","date_gmt":"2025-07-31T12:57:24","guid":{"rendered":"https:\/\/discover.restek.com\/?p=3268"},"modified":"2025-12-08T23:24:15","modified_gmt":"2025-12-08T23:24:15","slug":"how-do-i-address-an-increase-in-back-pressure-and-other-signs-of-blockage-or-contamination","status":"publish","type":"post","link":"https:\/\/discover.restek.com\/ja\/faq-ja\/gnot5055\/how-do-i-address-an-increase-in-back-pressure-and-other-signs-of-blockage-or-contamination","title":{"rendered":"How do I address an increase in back pressure and other signs of blockage or contamination?"},"content":{"rendered":"\n

Please follow the recommendations in our blog\u00a0“Building up Pressure on HPLC?<\/a>” This will help you identify or confirm the source of pressure. If the column itself is found to be the source of difficulty, please follow the column regeneration steps given on our\u00a0LC Column Cleaning Recommendations<\/a>\u00a0page. To help avoid future occurrences, Restek highly recommends the use of guard columns to protect your reversed-phase and normal-phase analytical LC columns from both frit blockage and column contamination.<\/p>\n","protected":false},"excerpt":{"rendered":"

Please follow the recommendations in our blog\u00a0“Building up Pressure on HPLC?” This will help you identify or confirm the source of pressure. If the column itself is found to be the source of difficulty, please follow the column regeneration steps given on our\u00a0LC Column Cleaning Recommendations\u00a0page. To help avoid future occurrences, Restek highly recommends the…<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"footnotes":""},"categories":[804],"tags":[2698,2682],"industries-application":[],"post-badge":[],"resource-type":[],"product-library":[],"resource-technique":[],"ppma_author":[414],"class_list":["post-3268","post","type-post","status-publish","format-standard","hentry","category-faq-ja","tag-faq-general-hplc","tag-faq-hplc-and-uhplc"],"acf":[],"taxonomy_info":{"category":[{"value":804,"label":"FAQ"}],"post_tag":[{"value":2698,"label":"FAQ: General HPLC"},{"value":2682,"label":"FAQ: HPLC and UHPLC"}]},"featured_image_src_large":false,"author_info":{"display_name":"Restek Corporation","author_link":"https:\/\/discover.restek.com\/ja\/author\/restek-corporation\/"},"comment_info":0,"category_info":[{"term_id":804,"name":"FAQ","slug":"faq-ja","term_group":0,"term_taxonomy_id":804,"taxonomy":"category","description":"","parent":0,"count":271,"filter":"raw","cat_ID":804,"category_count":271,"category_description":"","cat_name":"FAQ","category_nicename":"faq-ja","category_parent":0}],"tag_info":[{"term_id":2698,"name":"FAQ: General HPLC","slug":"faq-general-hplc","term_group":0,"term_taxonomy_id":2698,"taxonomy":"post_tag","description":"Browse general frequently asked questions for HPLC.","parent":0,"count":8,"filter":"raw"},{"term_id":2682,"name":"FAQ: HPLC and UHPLC","slug":"faq-hplc-and-uhplc","term_group":0,"term_taxonomy_id":2682,"taxonomy":"post_tag","description":"Browse frequently asked questions for HPLC and UHPLC products.","parent":0,"count":61,"filter":"raw"}],"authors":[{"term_id":414,"user_id":11,"is_guest":0,"slug":"restek-corporation","display_name":"Restek Corporation","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/Restek_Favicon_300x300.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/Restek_Favicon_300x300.jpg"},"0":null,"1":"","2":"","3":"","4":"","5":"","6":"","7":"","8":""}],"_links":{"self":[{"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/posts\/3268","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/comments?post=3268"}],"version-history":[{"count":2,"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/posts\/3268\/revisions"}],"predecessor-version":[{"id":70468,"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/posts\/3268\/revisions\/70468"}],"wp:attachment":[{"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/media?parent=3268"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/categories?post=3268"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/tags?post=3268"},{"taxonomy":"industries-application","embeddable":true,"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/industries-application?post=3268"},{"taxonomy":"post-badge","embeddable":true,"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/post-badge?post=3268"},{"taxonomy":"resource-type","embeddable":true,"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/resource-type?post=3268"},{"taxonomy":"product-library","embeddable":true,"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/product-library?post=3268"},{"taxonomy":"resource-technique","embeddable":true,"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/resource-technique?post=3268"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/discover.restek.com\/ja\/wp-json\/wp\/v2\/ppma_author?post=3268"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}