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PFAS Analysis by ISO 23702-1:2023 for Leather

03 Oct 2025

feature GNAR4301
  • Sample Matrix: leather
  • Sample Preparation: methanol extraction
  • Detection Technique: LC-MS/MS

Determination of the nonvolatile compound content by extraction method using liquid chromatography/ tandem mass spectrometry detector (LC-MS/MS)

ISO 23702-1:2023 is used for the analysis of 42 PFAS in leather. It is not available from Restek but may be purchased from other sources. The full analyte list and recommended products for ISO 23702-1:2023 are provided below. In addition, you can register and directly compare analyte lists and matrices across PFAS analysis methods here or visit www.restek.com/PFAS to explore our technical resources for PFAS analysis.

Analyte List for ISO 23702-1:2023 for PFAS Analysis

PFAS acronyms, compound names, and CAS numbers vary across methods and guidelines, and they also depend on compound form (e.g., neutral vs. salt). The following list uses standardized terminology to allow easy comparison across the methods and guidelines in our comprehensive guide. Please refer to ISO 23702-1:2023 for method-specific nomenclature.

AcronymPFAS NameCAS
PFBSPerfluoro-1-butanesulfonic acid375-73-5
PFDAPerfluorodecanoic acid335-76-2
PFDoAPerfluorododecanoic acid307-55-1
PFHpA*Perfluoroheptanoic acid375-85-9
PFHxSPerfluoro-1-hexanesulfonic acid355-46-4
PFHxAPerfluorohexanoic acid307-24-4
PFNAPerfluorononanoic acid375-95-1
PFOSPerfluorooctanesulfonic acid1763-23-1
PFOSFHeptadecafluorooctanesulfonyl fluoride307-35-7
PFOAPerfluorooctanoic acid335-67-1
Me-PFOAMethyl perfluorooctanoate376-27-2
Et-PFOAEthyl perfluorooctanoate3108-24-5
PF-3,7-DMOAPerfluoro(3,7-dimethyloctanoic acid)172155-07-6
PFTeDAPerfluorotetradecanoic acid376-06-7
PFTrDAPerfluorotridecanoic acid72629-94-8
PFUnAPerfluoroundecanoic acid2058-94-8
HFPO-DA, GenXHexafluoropropylene oxide dimer acid13252-13-6
PFBA*Perfluorobutanoic acid375-22-4
PFPeA*Perfluoropentanoic acid2706-90-3
PFDS*Perfluoro-1-decanesulfonic acid335-77-3
PFHpS*Perfluoro-1-heptanesulfonic acid375-92-8
FOSAPerfluoro-1-octanesulfonamide754-91-6
4:2 FTS*1H,1H,2H,2H-Perfluorohexane sulfonic acid757124-72-4
6:2 FTS*1H,1H,2H,2H-Perfluorooctane sulfonic acid27619-97-2
8:2 FTS1H,1H,2H,2H-Perfluorodecane sulfonic acid39108-34-4
10:2 FTS*1H,1H,2H,2H-perfluorododecane sulfonate (10:2)120226-60-0
NMeFOSAN-Methylperfluorooctanesulfonamide31506-32-8
NEtFOSAN-Ethylperfluorooctanesulfonamide4151-50-2
NMeFOSE2-(N-methylperfluoro-1-octanesulfonamido)-ethanol24448-09-7
NEtFOSE2-(N-ethylperfluoro-1-octanesulfonamido)-ethanol1691-99-2
8:3 FTCA2H,2H,3H,3H-Heptadecafluoroundecanoic acid34598-33-9
10:2 FTOH1H,1H,2H,2H-Perfluorododecan-1-ol or 2-(Perfluorodecyl)ethanol865-86-1
8:2 FTOH1H,1H,2H,2H-Perfluoro-1-decanol678-39-7
6:2 FTOH*3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol or 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluoro-1-octanol647-42-7
4:2 FTOH*1H,1H,2H,2H-Perfluorohexan-1-ol or 1-Hexanol2043-47-2
6:2 FTA*1H,1H,2H,2H-Perfluorooctyl acrylate17527-29-6
8:2 FTA1H,1H,2H,2H-Perfluorodecyl acrylate27905-45-9
10:2 FTA1H,1H,2H,2H-Perfluorododecyl acrylate17741-60-5
6:2 FTMA*1H,1H,2H,2H-heptadecafluorooctylmethacrylate2144-53-8
8:2 FTMA1H,1H,2H,2H-heptadecafluorodecylmethacrylate1996-88-9
7HPFHpA*7H-Dodecafluoroheptanoic acid1546-95-8
1-Decanaminium, N-decyl-N, N dimethyl-0,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-1-octanesulfonate251099-16-8

*Optional compound

Recommended Products for ISO 23702-1:2023 for PFAS Analysis

Analytical LC Columns:


Raptor C18, 2.7 µm, 50 x 2.1 mm HPLC Column
Force C18, 1.8 µm, 50 x 2.1 mm LC Column

Delay Columns:


PFAS Delay Column, 5 µm, 50 x 2.1 mm HPLC Column

PFAS delay column: 5 µm, 50 x 3.0 mm (cat.# 580959 [custom product])

Guard Columns:


UltraShield UHPLC PreColumn Filter, 0.2 µm Frit, ea.
EXP Direct Connect Holder for EXP Guard Cartridges, Includes Fitting & Ferrules
Raptor C18 EXP Guard Column Cartridge, 2.7 µm, 5 x 2.1 mm, 3-pk.

Sample Prep:


25 mm Syringe Filter, 0.22 µm, Polypropylene, Blue, Luer-Lock, 100-pk.
Q-sep Multispeed Centrifuge for QuEChERS

Vacuum Manifolds:


Resprep QR-24 Vacuum Manifold
Resprep QR-12 Vacuum Manifold

Vacuum Pumps:


Chemker 300 PTFE Vacuum Pump, 20 L/min, AC110 V, 60 Hz
Chemker 300 PTFE Vacuum Pump, 18 L/min, AC220 V, 50 Hz

General Lab Supplies:


Limited-Volume Screw-Thread Polypropylene Vials, 9 mm, 700 µL, 12 x 32 mm, 100-pk.
Limited-Volume Screw-Thread Polypropylene Vials, 9 mm, 700 µL, 12 x 32 mm, 1000-pk.
2.0 mL, 9 mm Solid-Top Polyethylene Caps, Screw-Thread, 10 mil thick membrane, Clear, 100-pk.
2.0 mL, 9 mm Solid-Top Polyethylene Caps, Screw-Thread, 10 mil thick membrane, Clear, 1000-pk.
Empty Centrifuge Tubes, 50 mL, Polypropylene w/Cap, 50-pk.
Empty Centrifuge Tubes, 50 mL, Polypropylene w/Cap, 500-pk.
Norm-Ject Plastic Syringe, 10 mL Luer Lock Tip, 100-pk.
Norm-Ject Plastic Syringe, 5 mL Luer Lock Tip, 100-pk.

Discover More Solutions for PFAS Analysis!

EZLC modeler PFAS Placeholder Image

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GNAR4301
Version: A