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Improving Liquid Chromatography (LC) Column Connections

20 Oct 2020

A good connection is necessary for trouble-free chromatography. Connecting incompatible fittings from different manufacturers can result in leaks, poor peak shape, and increased void volume (Figure 1). Each type of end-fitting has a unique seat depth or style. Generally, Restek, Valco, Parker, and Upchurch Scientific fittings are interchangeable; whereas Waters, SSI, Rheodyne, and Gasukura fittings are not (Figure 2).

Our wrenchless universal 10-32 PEEK column connector (cat.# 25015) can be used with any style of end fitting, and all 1/16-inch tubing. It is reusable and will adjust to any seat, depth, or style.

Figure 1: Incompatible fittings create problems

lighting

Figure 2: Fitting styles differ among various manufacturers.

illustration of Parker fitting with 10-32 threads
Parker
illustration of Valco fitting with 10-32 threads
Valco
illustration of Waters fitting with 10-32 threads
Waters
illustration of Rheodyne fitting with 10-32 threads
Rheodyne
illustration of Swagelok, Parker A-Lok fittings with 10-32 threads
Swagelok
Parker A- Lok

Products Mentioned


PEEK Column Connector (Beige, Round Body), Universal, 10-pk.

Author

  • Restek Corporation

    Restek is a leading provider of chromatography columns, accessories, and certified reference materials. Trust Restek for reliable, high-quality analytical solutions.

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