Samples or standards within a pH range of 5 < sample < 9 should not damage a capillary column. Repeated injections of samples with a pH between 4 and 5, or between 9 and 10, might cause column damage. Samples with a pH < 4 or > 10 should be diluted or neutralized before injection, as they will damage a column.
Can I inject acids or bases onto my polysiloxane column? Will they damage the column?
31 Jul 2025
Author
GNOT5021
