Cartridges may be processed by any of the techniques shown below.

A. Vacuum Manifold
The most common way to process SPE cartridges is to use an SPE vacuum manifold along with a vacuum source, such as a house vacuum, or a Chemker oil-free vacuum/pressure station. If you are using a well plate SPE product, a vacuum manifold specifically designed for well plates, such as the Resprep VM-96 vacuum manifold, can be used to process your SPE well plate.
B. Positive Pressure
The positive pressure technique uses an appropriate syringe (with a male luer fitting) along with the correct size SPE cartridge connector. An electronically controlled or air-actuated positive pressure system can also be used to process either a well plate or multiple cartridges at once.
C. Vacuum-Sidearm Flask
A vacuum-sidearm flask, along with a water faucet for aspiration, takes advantage of the Venturi effect. A standard vacuum source can also be used.

