Solid phase extraction (SPE) stands as a valuable sample preparation technique for water samples, utilized in the extraction of substances such as PFAS and semi-volatiles from drinking water. Despite its efficacy, SPE encounters challenges in non-drinking water matrices where solid particles can obstruct SPE cartridges, prolonging extraction or necessitating multiple cartridges per sample. EPA Method 1633 recently introduced glass wool to address this issue; however, manually adding wool can be laborious and inconsistent. This presentation introduces an integrated filter aid for SPE cartridges, enhancing consistency compared to glass wool. Incorporating the filter aid mitigates matrix-related clogging, leading to expedited extraction, reduced cartridge consumption, and more reliable analytical outcomes.
Mitigating Matrix Issues via Filter Aid to Improve Solid-Phase Extraction Methods
05 Nov 2025
Authors
GNOT5270
