{"id":84067,"date":"2026-01-22T20:48:33","date_gmt":"2026-01-22T20:48:33","guid":{"rendered":"https:\/\/discover.restek.com\/?p=84067"},"modified":"2026-01-22T20:48:37","modified_gmt":"2026-01-22T20:48:37","slug":"consolidating-lc-ms-ms-method-conditions-for-the-analysis-of-alcohol-metabolites-barbiturates-and-drugs-of-abuse-3","status":"publish","type":"post","link":"https:\/\/discover.restek.com\/zh-hans\/posters-presentations-it\/gnot5371\/consolidating-lc-ms-ms-method-conditions-for-the-analysis-of-alcohol-metabolites-barbiturates-and-drugs-of-abuse-3","title":{"rendered":"Consolidating LC-MS\/MS Method Conditions for the Analysis of Alcohol Metabolites, Barbiturates, and Drugs of Abuse"},"content":{"rendered":"\n<p>Efficiency is key in toxicology laboratories where multiple drug panels must be run daily. Consolidating multiple drug panels into large, multi-class drug assays can streamline the analytical testing process and reduce operating costs. To simplify the analysis of alcohol metabolites, barbiturates, THC metabolites, and drugs of abuse, three different LC-MS\/MS methods were developed for each analyte class using the same analytical column and mobile phases.<\/p>\n\n\n\n<p>A panel of 100 drugs of abuse, novel psychoactive substances, therapeutic drugs and metabolites, a panel of biomarkers of alcohol consumption, and a panel of barbiturates and cannabinoid metabolites were all analyzed using the same analytical column and mobile phase set up.<\/p>\n\n\n\n<p>This work highlights the ability of one LC-MS\/MS setup to analyze multiple toxicology panels. This allows for laboratories to simplify testing procedures, save time, and reduce operating costs.<\/p>\n\n\n\n<div data-wp-interactive=\"core\/file\" class=\"wp-block-file\"><object data-wp-bind--hidden=\"!state.hasPdfPreview\" hidden class=\"wp-block-file__embed\" data=\"https:\/\/discover.restek.com\/wp-content\/uploads\/poster-soft-2024-Consolidating-LC-MSMS-Method-Conditions-for-the-Analysis-of-Alcohol-Metabolites-Barbiturates-and-Drugs-of-Abuse.pdf\" type=\"application\/pdf\" style=\"width:100%;height:600px\" aria-label=\"Embed of poster-soft-2024-Consolidating LC-MSMS Method Conditions for the Analysis of Alcohol Metabolites, Barbiturates, and Drugs of Abuse.\"><\/object><a id=\"wp-block-file--media-bbd66920-7b9e-441b-94ea-897e4e670a60\" href=\"https:\/\/discover.restek.com\/wp-content\/uploads\/poster-soft-2024-Consolidating-LC-MSMS-Method-Conditions-for-the-Analysis-of-Alcohol-Metabolites-Barbiturates-and-Drugs-of-Abuse.pdf\">poster-soft-2024-Consolidating LC-MSMS Method Conditions for the Analysis of Alcohol Metabolites, Barbiturates, and Drugs of Abuse<\/a><a href=\"https:\/\/discover.restek.com\/wp-content\/uploads\/poster-soft-2024-Consolidating-LC-MSMS-Method-Conditions-for-the-Analysis-of-Alcohol-Metabolites-Barbiturates-and-Drugs-of-Abuse.pdf\" class=\"wp-block-file__button wp-element-button\" download aria-describedby=\"wp-block-file--media-bbd66920-7b9e-441b-94ea-897e4e670a60\">Download<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Efficiency is key in toxicology laboratories where multiple drug panels must be run daily. Consolidating multiple drug panels into large, multi-class drug assays can streamline the analytical testing process and reduce operating costs. To simplify the analysis of alcohol metabolites, barbiturates, THC metabolites, and drugs of abuse, three different LC-MS\/MS methods were developed for each&#8230;<\/p>\n","protected":false},"author":53,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"footnotes":""},"categories":[813],"tags":[],"industries-application":[],"post-badge":[],"resource-type":[],"product-library":[],"resource-technique":[],"hf_cat_post":[],"ppma_author":[608,579,432,702],"class_list":["post-84067","post","type-post","status-publish","format-standard","hentry","category-posters-presentations-it"],"acf":[],"taxonomy_info":{"category":[{"value":813,"label":"Posters &amp; Presentations"}]},"featured_image_src_large":false,"author_info":{"display_name":"Paul Connolly","author_link":"https:\/\/discover.restek.com\/zh-hans\/author\/paul-connolly\/"},"comment_info":0,"category_info":[{"term_id":813,"name":"Posters &amp; Presentations","slug":"posters-presentations-it","term_group":0,"term_taxonomy_id":813,"taxonomy":"category","description":"","parent":0,"count":118,"filter":"raw","cat_ID":813,"category_count":118,"category_description":"","cat_name":"Posters &amp; Presentations","category_nicename":"posters-presentations-it","category_parent":0}],"tag_info":false,"authors":[{"term_id":608,"user_id":53,"is_guest":0,"slug":"paul-connolly","display_name":"Paul Connolly","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-connolly-paul.png","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-connolly-paul.png"},"0":null,"1":"","2":"","3":"","4":"","5":"","6":"","7":"","8":""},{"term_id":579,"user_id":47,"is_guest":0,"slug":"jamie-l-york-phd","display_name":"Jamie L. York, PhD","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/york-jamie-1000x1000-1-e1765483005988.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/york-jamie-1000x1000-1-e1765483005988.jpg"},"0":null,"1":"","2":"","3":"","4":"","5":"","6":"","7":"","8":""},{"term_id":432,"user_id":13,"is_guest":0,"slug":"haley-berkland-ms","display_name":"Haley Berkland, MS","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-berkland-haley.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-berkland-haley.jpg"},"0":null,"1":"","2":"","3":"","4":"","5":"","6":"","7":"","8":""},{"term_id":702,"user_id":0,"is_guest":1,"slug":"justin-steimling","display_name":"Justin Steimling","avatar_url":"https:\/\/secure.gravatar.com\/avatar\/?s=96&d=mm&r=g","0":null,"1":"","2":"","3":"","4":"","5":"","6":"","7":"","8":""}],"_links":{"self":[{"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/posts\/84067","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/users\/53"}],"replies":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=84067"}],"version-history":[{"count":1,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/posts\/84067\/revisions"}],"predecessor-version":[{"id":84069,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/posts\/84067\/revisions\/84069"}],"wp:attachment":[{"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=84067"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=84067"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=84067"},{"taxonomy":"industries-application","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/industries-application?post=84067"},{"taxonomy":"post-badge","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/post-badge?post=84067"},{"taxonomy":"resource-type","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/resource-type?post=84067"},{"taxonomy":"product-library","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/product-library?post=84067"},{"taxonomy":"resource-technique","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/resource-technique?post=84067"},{"taxonomy":"hf_cat_post","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/hf_cat_post?post=84067"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/ppma_author?post=84067"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}