{"id":90556,"date":"2026-03-20T19:40:06","date_gmt":"2026-03-20T19:40:06","guid":{"rendered":"https:\/\/discover.restek.com\/?p=90556"},"modified":"2026-03-20T19:40:10","modified_gmt":"2026-03-20T19:40:10","slug":"importance-of-gc-column-deactivation-technology-in-the-analysis-of-challenging-compounds","status":"publish","type":"post","link":"https:\/\/discover.restek.com\/zh-hans\/posters-presentations\/gnot5657\/importance-of-gc-column-deactivation-technology-in-the-analysis-of-challenging-compounds","title":{"rendered":"Importance of GC Column Deactivation Technology in the Analysis of Challenging Compounds"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">A recent advancement in gas chromatography (GC) column deactivation balances chromatographic performance of acidic, basic and neutral analytes at trace level concentrations. Deactivation is a critical step in GC column manufacturing that modifies the fused silica capillary surface activity to promote coating and adhesion. Residual surface silanols, which result from contamination or incomplete deactivation, adsorb acidic and basic compounds, contributing to peak area loss or tailing. Deactivation procedures vary between products and manufacturers, with individual benefits and drawbacks that become exacerbated during sensitive applications. There is increasing demand to improve identification and quantification of reactive analytes with complex or consolidated methodologies. TriMax deactivation technology improves polymer adhesion and minimizes residual surface activity for a long lasting, broadly inert surface. Columns built with the new GC deactivation technology were challenged with a wide variety of applications, and against traditional 5-type columns. Overall, the TriMax deactivation presents an advancement over traditional GC columns, providing unparalleled inertness to a broader range of acids, bases, and neutrals. These improvements offer opportunity for method consolidation and trace level analysis that would not be successful with traditional technology.<\/p>\n\n\n\n<div data-wp-interactive=\"core\/file\" class=\"wp-block-file\"><object data-wp-bind--hidden=\"!state.hasPdfPreview\" hidden class=\"wp-block-file__embed\" data=\"https:\/\/discover.restek.com\/wp-content\/uploads\/poster-pittcon-2026-RMX-deactivation.pdf\" type=\"application\/pdf\" style=\"width:100%;height:600px\" aria-label=\"Embed of poster-pittcon-2026-RMX-deactivation.\"><\/object><a id=\"wp-block-file--media-340ef431-2622-443e-9790-7df052579335\" href=\"https:\/\/discover.restek.com\/wp-content\/uploads\/poster-pittcon-2026-RMX-deactivation.pdf\">poster-pittcon-2026-RMX-deactivation<\/a><a href=\"https:\/\/discover.restek.com\/wp-content\/uploads\/poster-pittcon-2026-RMX-deactivation.pdf\" class=\"wp-block-file__button wp-element-button\" download aria-describedby=\"wp-block-file--media-340ef431-2622-443e-9790-7df052579335\">Download<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>A recent advancement in gas chromatography (GC) column deactivation balances chromatographic performance of acidic, basic and neutral analytes at trace level concentrations. Deactivation is a critical step in GC column manufacturing that modifies the fused silica capillary surface activity to promote coating and adhesion.<\/p>\n","protected":false},"author":70,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"footnotes":""},"categories":[12],"tags":[],"industries-application":[],"post-badge":[],"resource-type":[],"product-library":[],"resource-technique":[],"ppma_author":[2657,452,441,765,438,447,454],"class_list":["post-90556","post","type-post","status-publish","format-standard","hentry","category-posters-presentations"],"acf":[],"taxonomy_info":{"category":[{"value":12,"label":"Posters &amp; Presentations"}]},"featured_image_src_large":false,"author_info":{"display_name":"Ramkumar Dhandapani, PhD","author_link":"https:\/\/discover.restek.com\/zh-hans\/author\/ramkumar-dhandapani-phd\/"},"comment_info":0,"category_info":[{"term_id":12,"name":"Posters &amp; Presentations","slug":"posters-presentations","term_group":0,"term_taxonomy_id":12,"taxonomy":"category","description":"","parent":0,"count":118,"filter":"raw","cat_ID":12,"category_count":118,"category_description":"","cat_name":"Posters &amp; Presentations","category_nicename":"posters-presentations","category_parent":0}],"tag_info":false,"authors":[{"term_id":2657,"user_id":70,"is_guest":0,"slug":"ramkumar-dhandapani-phd","display_name":"Ramkumar Dhandapani, PhD","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/Dhandapani_Ramkumar_Profile.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/Dhandapani_Ramkumar_Profile.jpg"},"author_category":"1","first_name":"Ramkumar","last_name":"Dhandapani","user_url":"","job_title":"Director of Product Management","description":"Dr. Ramkumar Dhandapani\u00a0is a seasoned analytical chemist with over\u00a023 years of experience\u00a0in the chromatography industry and a Ph.D. in analytical chemistry. During his career, he has specialized in method development, validation, and the troubleshooting of chromatography methods. He has developed numerous regulatory-compliant methods across diverse sectors, including\u00a0environmental analysis, food quality and safety, pharmaceutical, fuels, and chemical industries. Currently, Dr. Dhandapani is the Director of Product Management at Restek, he is keen on innovation in chromatography and scaling breakthrough innovations\u00a0to market as commercial products."},{"term_id":452,"user_id":32,"is_guest":0,"slug":"colton-myers","display_name":"Colton Myers","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-myers-colton.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-myers-colton.jpg"},"author_category":"1","first_name":"Colton","last_name":"Myers","user_url":"https:\/\/www.linkedin.com\/in\/myerscolton\/","job_title":"Product Manager - New Product Development","description":"Colton Myers is a Product Manager for GC columns at Restek Corporation with over 10 years of experience in research and development. He specializes in driving new GC column technologies from concept to market, combining deep technical expertise with a strong focus on innovation and commercialization. Colton holds a BS in chemistry from Juniata College and a Master of Management in Corporate Innovation and Entrepreneurship from Penn State University."},{"term_id":441,"user_id":21,"is_guest":0,"slug":"chris-english","display_name":"Chris English","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-english-chris.png","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-english-chris.png"},"author_category":"1","first_name":"Chris","last_name":"English","user_url":"https:\/\/www.linkedin.com\/in\/chris-english-28214912\/","job_title":"Sr. R&D Manager","description":"Since 2004, Chris has managed a team of chemists in Restek's innovations laboratory who perform new product testing, method development, and applications work. Before taking the reins of our lab, he spent seven years as an environmental chemist and was critical to the development of Restek\u2019s current line of volatile GC columns. Prior to joining Restek, he operated a variety of gas chromatographic detectors conducting method development and sample analysis. Chris holds a BS in environmental science from Saint Michael's College."},{"term_id":765,"user_id":0,"is_guest":1,"slug":"victoria-r-zeger","display_name":"Victoria R. Zeger","avatar_url":"https:\/\/secure.gravatar.com\/avatar\/?s=96&d=mm&r=g","author_category":"1","first_name":"Victoria R.","last_name":"Zeger","user_url":"","job_title":"","description":"Department of Chemistry, Iowa State University, Ames, IA 50011, USA"},{"term_id":438,"user_id":18,"is_guest":0,"slug":"jessi-collier","display_name":"Jessi Collier","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-collier-jessi.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-collier-jessi.jpg"},"author_category":"1","first_name":"Jessi","last_name":"Collier","user_url":"","job_title":"","description":"Jessi is an advanced scientist in the GC applications group where her work focuses on environmental and food contaminants. Prior to joining Restek in 2023, she worked for the Mississippi State Chemical Lab as a pesticide residue analyst, primarily testing regulatory samples, agricultural samples, environmental samples, foods, and other consumer products via GC-MS, GC-MS\/MS, GC-FID, and GC-ECD. Jessi holds a BS in chemistry and a BA in Mandarin Chinese from Mississippi State University."},{"term_id":447,"user_id":27,"is_guest":0,"slug":"jason-hoisington","display_name":"Jason Hoisington","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-hoisington-jason-01.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-hoisington-jason-01.jpg"},"author_category":"1","first_name":"Jason","last_name":"Hoisington","user_url":"","job_title":"","description":"Jason Hoisington received his bachelor\u2019s degree in general science with a focus on chemistry from the University of Alaska, Fairbanks. He worked for SGS Environmental for seven years in environmental soil and water testing, developing methods for the analysis of volatiles and semivolatile organics to include pesticides and polychlorinated biphenyls (PCBs). In 2012, Jason moved on to lab and application support for Dow Chemical Company, providing advanced analytical troubleshooting and method development. In 2019, Jason joined Restek and has focused on air applications."},{"term_id":454,"user_id":34,"is_guest":0,"slug":"erica-pack-phd","display_name":"Erica Pack, PhD","avatar_url":{"url":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-pack-erica.jpg","url2x":"https:\/\/discover.restek.com\/wp-content\/uploads\/people-pack-erica.jpg"},"author_category":"1","first_name":"Erica","last_name":"Pack","user_url":"https:\/\/www.linkedin.com\/in\/ericapack\/","job_title":"","description":"Erica is an interdisciplinary GC applications and technologies scientist at Restek. She obtained her bachelor's degree in forensic biology from The Pennsylvania State University, and her doctorate from Virginia Tech in plant pathology, physiology, and weed science. Since joining Restek in 2021, she has worked with a wide variety of GC columns, including fused silica, MXT, PLOT, and packed columns as well as accessories, such as liners, valves, and methanizers."}],"_links":{"self":[{"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/posts\/90556","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/users\/70"}],"replies":[{"embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=90556"}],"version-history":[{"count":1,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/posts\/90556\/revisions"}],"predecessor-version":[{"id":90558,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/posts\/90556\/revisions\/90558"}],"wp:attachment":[{"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=90556"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/categories?post=90556"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/tags?post=90556"},{"taxonomy":"industries-application","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/industries-application?post=90556"},{"taxonomy":"post-badge","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/post-badge?post=90556"},{"taxonomy":"resource-type","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/resource-type?post=90556"},{"taxonomy":"product-library","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/product-library?post=90556"},{"taxonomy":"resource-technique","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/resource-technique?post=90556"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/discover.restek.com\/zh-hans\/wp-json\/wp\/v2\/ppma_author?post=90556"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}