Yes. Some degree of retention time shifting is usually observed between LPGC column kits. Depending on the approach used or the width of the monitoring retention time windows, some adjustment may be necessary upon installation of a new LPGC column kit. However, the retention times should stay within the expected stability range throughout the lifetime of the column kit.
My retention times shifted when I installed a new LPGC column kit. Is that normal?
30 Jul 2025
Author
GNOT5115
