Perfluoroalkyl substances (PFAS) are a group of man-made chemicals widely used in industrial applications and consumer products. Their widespread usage and resistance to degradation has resulted in PFAS being a ubiquitous environmental contaminant, and the potential health effects is of growing concern. While many of the long-chain PFAS have been recognized as harmful, alternative compounds have emerged in their place. Short-chain PFAS compounds are considered to be less bioaccumulative and toxic than long-chain PFAS, but their widespread use has resulted in their increased environmental accumulation. In this work, several methods will be outlined to meet the evolving landscape of PFAS analysis. These methods include EPA methods 1633, 533, 8327, and 537.1 as well as a method for the analysis of ultra-short through short-chain(C1-C4) PFAS using a unique hybrid HILIC/ion-exchange stationary phase.
The Evolving Landscape of PFAS Detection, an Outline of Methods
07 Nov 2025
Author
GNOT5314
