Posters & Presentations

Highly Efficient LC-MS/MS Analysis of Multiple Mycotoxins Utilizing Biphenyl Column Selectivity with Inert Column Technology

07 Nov 2025

Organophosphorus pesticides (OPPs) play a pivotal role in modern agriculture, aiding in pest control and enhancing crop yield. OPPs are inexpensive and efficient and account for a significant portion of pesticides used globally. Despite their benefits, these pesticides are toxic, and their extensive use raises concerns regarding environmental contamination and human health risks. Therefore, careful analysis and monitoring is necessary.

However, the analysis faces sensitivity and recovery issues due to their reactivity with metal surfaces in conventional columns, resulting in tailing peaks and low sensitivity. In this work, Restek looks to establish the benefits of coated column technologies by comparing methods developed on inert and standard stainless-steel hardware. The coating combined with our selective stationary phases resulted in exceptional analyte recoveries, lower detection limits, and better peak shape. The signal heights and areas compared to conventional columns were doubled. In addition, time-consuming conditioning and complicated passivation belong to the past.

Authors

  • Tina Brandscher

    Tina has over ten years of experience in analytical chemistry and method development with four years of practical experience in method development and routine analysis of contaminants and mycotoxins in plant-based foodstuffs and pharmaceuticals. Additionally, she has four years of practical experience in environmental analysis. Tina joined the German sales team at Restek GmbH in 2022, and after one and a half years as a sales rep in southeast Germany, became part of the LC specialist team in the EMEA region.

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  • Paul Connolly
  • Diego López

    Diego is the product manager for sample preparation at Restek Corporation. He has over 10 years of experience in liquid chromatography for both chiral and achiral separations and holds a PhD in chemistry from The University of Texas at Arlington.

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