Solid phase extraction (SPE) stands as a valuable sample preparation technique for water samples utilised in the extraction of substances, such as PFAS and semivolatiles from drinking water. Despite its efficacy, SPE encounters challenges in nondrinking water matrices where solid particles can obstruct SPE cartridges, prolonging extraction or necessitating multiple cartridges per sample. EPA Method 1633 recently introduced glass wool to address this issue; however, manually adding wool can be laborious and inconsistent. This presentation introduces an integrated filter aid for SPE cartridges, enhancing consistency compared to glass wool. Incorporating the filter aid mitigates matrix-related clogging, leading to expedited extraction, reduced cartridge consumption, and more reliable analytical outcomes.
Mitigating Matrix Issues via Filter Aid to Improve Solid-Phase Extraction Methods
07 Nov 2025
Authors
GNOT5302
