Posters & Presentations

Large Volume Injection of Pesticides Using Low-Pressure Gas Chromatography

22 Jan 2026

Concurrent Solvent Recondensation Large Sample Volume splitless injection (CSR-LVSI, or LVI) is a sample technique that overcomes the limitation of the maximum injection volume to 1 – 2 µL valid for classical splitless injection. Low Pressure Gas Chromatography is a novel technique that had been successfully used for pesticide screening and quantification. The LPGC configuration with the restrictor/guard column lends itself to the requirements of the CSR-LVSI and has a potential to improve the sensitivity and lower detection limits. Large volume injection of acetonitrile and acetonitrile – toluene samples were evaluated in range of 1 – 25 µL for peak shapes and the relationship between the peak area and injection volume was established.

Authors

  • Jana Hepner, PhD
  • Joe Konschnik
  • Jaap de Zeeuw

    Jaap is a world-renowned chromatographer with over 40 years of experience, including 15 years with Restek and 27 years with Varian/Chrompack prior to joining Restek. Throughout his career, Jaap has focused the chromatographic challenges of industrial analysis. For his 1979 graduation from The Institute for Higher Education, where he specialized in chemistry, Jaap authored a paper titled "The Challenge of Coating Flexible Fused Silica Capillary Columns" and has since distinguished himself as an authority on the subject. Jaap has been directly involved with the creation of numerous chemically bonded columns, including the first bonded PEG column and the stabilized PLOT columns widely used in the petrochemical arena. He has also helped develop new techniques, such as fast GC-MS using vacuum GC technology (low-pressure GC or LPGC). Over his innovative career, he has filed several patents for his work. Based out of the Netherlands, Jaap is extensively published and regularly travels internationally to share his knowledge. After retiring from Restek, Jaap founded CreaVisions, where he works as a GC Consultant and teaches master classes on key GC topics as well as on creativity in science.

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